Skip to main content
SpringerLink
Log in

Sleep and Quality of Life in Traumatic Brain Injury and Guillain–Barré Syndrome

  • Chapter
Sleep and Quality of Life in Clinical Medicine

  • 2427 Accesses

Summary

Sleep disorders in traumatic brain injury include insomnia, disruption of sleep architecture, excessive daytime sleepiness (EDS), and disorders of biological rhythms. Insomnia is common and is an important impediment to successful rehabilitation. Risk factors for insomnia in traumatic brain injury (TBI) include female gender, lesser degrees of injury, depression, and pain. EDS usually appears later in the course of illness than does insomnia. Circadian rhythm disturbances, particularly delayed sleep-phase syndrome, may present as insomnia. A number of reports have described behavioral aberrations in Guillain–Barré syndrome, a condition that targets mainly the peripheral nervous system. Hallucinations and oneiric experiences are among the behaviors seen in Guillain–Barré syndrome (GBS). These phenomena may be associated with reduced hypocretin-1 in the cerebrospinal fluid (csf) and with narcoleptic-like changes on polysomnography (PSG), suggesting the possibility of hypothalamic involvement in GBS.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bassetti C, Aldrich M. Sleep apnea in acute cerebrovascular diseases: final report on 128 patients. Sleep 1999;22(2):217–23.

    PubMed  CAS  Google Scholar 

  2. Trenkwalder C. Parkinsonism. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine, 4th ed. Philadelphia, PA: Elsevier Saunders; 2005:801–10.

    Google Scholar 

  3. Rye D. Sleepiness and unintended sleep in Parkinson’s disease. Curr Treat Options Neurol 2003;5(3):231–9.

    Article  PubMed  Google Scholar 

  4. Frucht S, Rogers JD, Greene PE, Gordon MF, Fahn S. Falling asleep at the wheel: motor vehicle mishaps in persons taking pramipexole and ropinirole. Neurology 1999;52(9):1908–10.

    PubMed  CAS  Google Scholar 

  5. Saunders J, Whitham R, Schaumann B. Sleep disturbance, fatigue, and depression in multiple sclerosis. Neurology 1991;41:320.

    Google Scholar 

  6. Shouse MN, Mahowald ML. Epilepsy, sleep, and sleep disorders. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine. 4th ed. Philadelphia, PA: Elsevier Saunders; 2005:863–78.

    Google Scholar 

  7. Bricolo A, Gentilomo A, Rosadini G, Rossi GF. Long-lasting post-traumatic unconsciousness. A study based on nocturnal EEG and polygraphic recording. Acta Neurol Scand 1968;44(4):513–32.

    PubMed  CAS  Google Scholar 

  8. Bergamini L, Bergamasco B, Doriguzzi T, Sacerdote I. Sleep electroencephalographic patterns as a prognostic criteria in post-traumatic coma. Electroencephalogr Clin Neurophysiol 1968;25(5):514.

    Article  PubMed  CAS  Google Scholar 

  9. Alexandre A, Colombo F, Nertempi P, Benedetti A. Cognitive outcome and early indices of severity of head injury. J Neurosurg 1983;59(5):751–61.

    PubMed  CAS  Google Scholar 

  10. George B, Landau-Ferey J. Twelve months’ follow-up by night sleep EEG after recovery from severe head trauma. Neurochirurgia (Stuttg) 1986;29(2):45–7.

    CAS  Google Scholar 

  11. Ron S, Algom D, Hary D, Cohen M. Time-related changes in the distribution of sleep stages in brain injured patients. Electroencephalogr Clin Neurophysiol 1980;48(4):432–41.

    Article  PubMed  CAS  Google Scholar 

  12. Clinchot DM, Bogner J, Mysiw WJ, Fugate L, Corrigan J. Defining sleep disturbance after brain injury. Am J Phys Med Rehabil 1998;77(4):291–5.

    Article  PubMed  CAS  Google Scholar 

  13. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC: American Psychiatric Association; 1994.

    Google Scholar 

  14. American Academy of Sleep Medicine. International Classification of Sleep Disorders: Diagnostic and Coding Manual. 2nd ed. Westchester, IL: American Academy of Sleep Medicine; 2005.

    Google Scholar 

  15. Fichtenberg NL, Zafonte RD, Putnam S, Mann NR, Millard AE. Insomnia in a post-acute brain injury sample. Brain Inj 2002;16(3):197–206.

    Article  PubMed  Google Scholar 

  16. Ohayon MM. Epidemiology of insomnia: what we know and what we still need to learn. Sleep Med Rev 2002;6:97–111.

    Article  PubMed  Google Scholar 

  17. Klink ME, Quan SF, Kaltenborn WT, Lebowitz MD. Risk factors associated with complaints of insomnia in a general adult population. Influence of previous complaints of insomnia. Arch Intern Med 1992;152(8):1634–7.

    Article  PubMed  CAS  Google Scholar 

  18. Fukuda N, Honma H, Kohsaka M, et al. Gender difference of slow wave sleep in middle aged and elderly subjects. Psychiatry Clin Neurosci 1999;53(2):151–3.

    Article  PubMed  CAS  Google Scholar 

  19. Hume KI, Van F, Watson A. A field study of age and gender differences in habitual adult sleep. J Sleep Res 1998;7(2): 85–94.

    Article  PubMed  CAS  Google Scholar 

  20. Voderholzer U, Al-Shajlawi A, Weske G, Feige B, Riemann D. Are there gender differences in objective and subjective sleep measures? A study of insomniacs and healthy controls. Depress Anxiety 2003;17(3):162–72.

    Article  PubMed  Google Scholar 

  21. Majerus S, Gill-Thwaites H, Andrews K, Laureys S. Behavioral evaluation of consciousness in severe brain damage. Prog Brain Res 2005;150:397–413.

    Article  PubMed  Google Scholar 

  22. Fichtenberg NL, Millis SR, Mann NR, Zafonte RD, Millard AE. Factors associated with insomnia among post-acute traumatic brain injury survivors. Brain Inj 2000;14(7):659–67.

    Article  PubMed  CAS  Google Scholar 

  23. Ouellet MC, Beaulieu-Bonneau S, Morin CM. Insomnia in patients with traumatic brain injury: frequency, characteristics, and risk factors. J Head Trauma Rehabil 2006;21(3): 199–212.

    Article  PubMed  Google Scholar 

  24. Parcell DL, Ponsford JL, Rajaratnam SM, Redman JR. Self-reported changes to nighttime sleep after traumatic brain injury. Arch Phys Med Rehabil 2006;87(2):278–85.

    Article  PubMed  Google Scholar 

  25. Beetar JT, Guilmette TJ, Sparadeo FR. Sleep and pain complaints in symptomatic traumatic brain injury and neurologic populations. Arch Phys Med Rehabil 1997;77(12):1298–302.

    Article  Google Scholar 

  26. Pillar G, Averbooch E, Katz N, Peled N, Kaufman Y, Shahar E. Prevalence and risk of sleep disturbances in adolescents after minor head injury. Pediatr Neurol 2003;29(2):131–5.

    Article  PubMed  Google Scholar 

  27. Benca RM. Mood disorders. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine. 4th ed. Philadelphia, PA: Elsevier Saunders; 2005:1314–8.

    Google Scholar 

  28. Kaufman Y, Tzischinsky O, Epstein R, Etzioni A, Lavie P, Pillar G. Long-term sleep disturbances in adolescents after minor head injury. Pediatr Neurol 2001;24(2):129–34.

    Article  PubMed  CAS  Google Scholar 

  29. Nauta WJH. Hypothalamic regulation of sleep in rats: An experimental study. J Neurophysiol 1946;9:285–316.

    Google Scholar 

  30. Tobe EH, Schneider JH, Mrozik T, Lidsky T. Persisting insomnia following traumatic brain injury. J Neuropsychiatry Clin Neurosci 1999;11(4):504–6.

    PubMed  CAS  Google Scholar 

  31. Baumann CR, Stocker R, Imhof HG, et al. Hypocretin-1 (orexin A) deficiency in acute traumatic brain injury. Neurology 2005;65(1):147–9.

    Article  PubMed  CAS  Google Scholar 

  32. Baumann CR, Bassetti C. Hypocretins (orexins): clinical impact of the discovery of a neurotransmitter. Sleep Med Rev 2005;9(4):253–68.

    Article  PubMed  Google Scholar 

  33. Nishino S, Ripley B, Overeem S, Lammers GJ, Mignot E. Hypocretin (orexin) deficiency in human narcolepsy. Lancet 2000;355(9197):39–40.

    Article  PubMed  CAS  Google Scholar 

  34. Mignot E, Lammers GJ, Ripley B, et al. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch Neurol 2002;59(10):1553–62.

    Article  PubMed  Google Scholar 

  35. Overeem S, Mignot E, van Dijk JG, Lammers GJ. Narcolepsy: clinical features, new pathophysiologic insights, and future perspectives. J Clin Neurophysiol 2001;18(2):78–105.

    Article  PubMed  CAS  Google Scholar 

  36. Dauvilliers Y, Baumann CR, Carlander B, et al. CSF hypocretin-1 levels in narcolepsy, Kleine-Levin syndrome, and other hypersomnias and neurological conditions. J Neurol Neurosurg Psychiatry 2003;74(12):1667–73.

    Article  PubMed  CAS  Google Scholar 

  37. Ouellet MC, Savard J, Morin CM. Insomnia following traumatic brain injury: a review. Neurorehabil Neural Repair 2004;18(4):187–98.

    Article  PubMed  Google Scholar 

  38. Li Pi Shan RS, Ashworth NL. Comparison of lorazepam and zopiclone for insomnia in patients with stroke and brain injury: a randomized, crossover, double-blinded trial. Am J Phys Med Rehabil 2004;83(6):421–7.

    Article  PubMed  Google Scholar 

  39. Schreiber S, Klag E, Gross Y, Segman RH, Pick CG. Beneficial effect of risperidone on sleep disturbance and psychosis following traumatic brain injury. Int Clin Psychopharmacol 1998;13(6):273–5.

    Article  PubMed  CAS  Google Scholar 

  40. Kemp S, Biswas R, Neumann V, Coughlan A. The value of melatonin for sleep disorders occurring post-head injury: a pilot RCT. Brain Inj 2004;18(9):911–9.

    Article  PubMed  Google Scholar 

  41. Krystal AD, Walsh JK, Laska E, et al. Sustained efficacy of eszopiclone over 6 months of nightly treatment: results of a randomized, double-blind, placebo-controlled study in adults with chronic insomnia. Sleep 2003;26(7):793–9.

    PubMed  Google Scholar 

  42. Ouellet MC, Morin CM. Cognitive behavioral therapy for insomnia associated with traumatic brain injury: a single-case study. Arch Phys Med Rehabil 2004;85(8):1298–302.

    Article  PubMed  Google Scholar 

  43. Jones BE. Basic mechanisms of sleep-wake states. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine. 4th ed. Philadelphia, PA: Elsevier Saunders; 2005:136–53.

    Google Scholar 

  44. Valente M, Placidi F, Oliveira AJ, et al. Sleep organization pattern as a prognostic marker of the subacute stage of post-traumatic coma. Clin Neurophysiol 2002;113(11):1798–805.

    Article  PubMed  CAS  Google Scholar 

  45. Giubilei F, Forminsano R, Fiorini M, et al. Sleep abnormalities in traumatic apallic syndrome. J Neurol Neurosurg Psychiatry 1995;58(4):484–6.

    PubMed  CAS  Google Scholar 

  46. D’Aleo G, Saltuari L, Gerstenbrand F, Bramanti P. Sleep in the last remission stages of vegetative state of traumatic nature. Funct Neurol 1994;9(4):189–92.

    PubMed  CAS  Google Scholar 

  47. Busek P, Faber J. The influence of traumatic brain lesion on sleep architecture. Sb Lek 2000;101(3):233–9.

    PubMed  CAS  Google Scholar 

  48. Evans BM, Bartlett JR. Prediction of outcome in severe head injury based on recognition of sleep related activity in the polygraphic electroencephalogram. J Neurol Neurosurg Psychiatry 1995;59 (1):17–25.

    PubMed  CAS  Google Scholar 

  49. Parsons LC, Crosby LJ, Perlis M, Britt T, Jones P. Longitudinal sleep EEG power spectral analysis studies in adolescents with minor head injury. J Neurotrauma 1997;14(8):549–59.

    PubMed  CAS  Google Scholar 

  50. Cohen M, Oksenberg A, Snir D, Stern M, Groswasser Z. Temporally related changes of sleep complaints in traumatic brain injured patients. J Neurol Neurosurg Psychiatry 1992;55(4):313–5.

    PubMed  CAS  Google Scholar 

  51. Masel BE, Scheibel RS, Kimbark T, Kuna ST. Excessive daytime sleepiness in adults with brain injuries. Arch Phys Med Rehabil 2001;82(11):1526–32.

    Article  PubMed  CAS  Google Scholar 

  52. Johns MW. Sleepiness in different situations measured by the Epworth Sleepiness Scale. Sleep 1994;17(8):703–10.

    PubMed  CAS  Google Scholar 

  53. Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res 1989;28(2):193–213.

    Article  PubMed  CAS  Google Scholar 

  54. Carskadon MA, Dement WC, Mitler MM, Roth T, Westbrook PR, Keenan S. Guidelines for the multiple sleep latency test (MSLT): a standard measure of sleepiness. Sleep 1986;9(4): 519–24.

    PubMed  CAS  Google Scholar 

  55. Guilleminault C, Faull KF, Miles L, van den Hoed J. Posttraumatic excessive daytime sleepiness: a review of 20 patients. Neurology 1983;33(12):1584–9.

    PubMed  CAS  Google Scholar 

  56. Guilleminault C, Yuen KM, Gulevich MG, Karadeniz D, Leger D, Philip P. Hypersomnia after head-neck trauma: a medicolegal dilemma. Neurology 2000;54(3):653–9.

    PubMed  CAS  Google Scholar 

  57. Castriotta RJ, Lai JM. Sleep disorders associated with traumatic brain injury. Arch Phys Med Rehabil 2001;82(10):1403–6.

    Article  PubMed  CAS  Google Scholar 

  58. Webster J, Bell KR, Hussey JD, Natale TK, Lakshminarayan S. Sleep apnea in adults with traumatic brain injury: a preliminary investigation. Arch Phys Med Rehabil 2001;82(3): 316–21.

    Article  PubMed  CAS  Google Scholar 

  59. Lankford DA, Wellman JJ, O’Hara C. Posttraumatic narcolepsy in mild to moderate closed head injury. Sleep 1994;17(8 Suppl):S25–8.

    PubMed  CAS  Google Scholar 

  60. Rogers AE, Meehan J, Guilleminault C, Grumet FC, Mignot E. HLA DR15 (DR2) and DQB1*0602 typing studies in 188 narcoleptic patients with cataplexy. Neurology 1997;48(6): 1550–6.

    PubMed  CAS  Google Scholar 

  61. Kapen S, Mohan K. Post traumatic narcolepsy. A report of three cases. Sleep Res 1995;24:259.

    Google Scholar 

  62. Good JL, Barry E, Fishman P. Posttraumatic narcolepsy: the complete syndrome with tissue typing. Case report. J Neurosurg 1989;71(5 Pt 1):765–7.

    PubMed  CAS  Google Scholar 

  63. Maccario M, Ruggles KH, Meriwether MW. Post-traumatic narcolepsy. Milit Med 1987;152(7):370–1.

    CAS  Google Scholar 

  64. Bruck D, Broughton RJ. Diagnostic ambibuities in a case of post-traumatic narcolepsy with cataplexy. Brain Inj 2004;18(3): 321–6.

    Article  PubMed  CAS  Google Scholar 

  65. Francisco GE, Ivanhoe CB. Successful treatment of post-traumatic narcolepsy with methylphenidate: a case report. Am J Phys Med Rehabil 1996;75(1):63–5.

    Article  PubMed  CAS  Google Scholar 

  66. Lin L, Faraco J, Kadotani H, et al. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell 1999;98(3):365–76.

    Article  PubMed  CAS  Google Scholar 

  67. Chemelli RM, Willie JT, Sinton CM, et al. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell 1999;98(4):437–51.

    Article  PubMed  CAS  Google Scholar 

  68. Nishino S, Kanbayashi T, Fujiki N, et al. CSF hypocretin levels in Guillain-Barré syndrome and other inflammatory neuropathies. Neurology 2003;61(12):823–25.

    PubMed  CAS  Google Scholar 

  69. Gooley JJ, Saper CB. Anatomy of the mammalian circadian system. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine. 4th ed. Philadelphia, PA: Elsevier Saunders; 2005:335–50.

    Google Scholar 

  70. Rosenwasser AM, Turek FW. Physiology of the mammalian circadian system. In: Kryger MH, ed. Principles and Practice of Sleep Medicine. 4th ed. Philadelphia, PA: Elsevier Saunders; 2005:351–63.

    Google Scholar 

  71. Czeisler CA, Buxton OM, Khalsa SBS. The human circadian timing system and sleep-wake regulation. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine. 4th ed. Philadelphia, PA: Elsevier Saunders; 2005: 375–94.

    Google Scholar 

  72. Weitzman ED, Czeisler CA, Coleman RM, et al. Delayed sleep phase syndrome. A chronobiological disorder with sleep-onset insomnia. Arch Gen Psychiatry 1981;38(7):737–46.

    PubMed  CAS  Google Scholar 

  73. Smits MG, Nagtegaal JE. Post-traumatic delayed sleep phase syndrome. Neurology 2000;55(6):902–3.

    PubMed  CAS  Google Scholar 

  74. Nagtegaal JE, Kerkhof GA, Smits MG, Swart AC, van der Meer YG. Traumatic brain injury-associated delayed sleep phase syndrome. Funct Neurol 1997;12(6):345–8.

    PubMed  CAS  Google Scholar 

  75. Patten SB, Lauderdale W. Delayed sleep phase disorder after traumatic brain injury. J Am Acad Child Adolesc Psychiatry 1992;31(1):100–2.

    Article  PubMed  CAS  Google Scholar 

  76. Quinto C, Gellido C, Chokroverty S, Masdeu J. Posttraumatic delayed sleep phase syndrome. Neurology 2000;54(1):250–2.

    PubMed  CAS  Google Scholar 

  77. Boivin DB, James FO, Santo JB, Caliyurt O, Chalk C. Non-24-hour sleep-wake syndrome following a car accident. Neurology 2003;60(11):1841–3.

    PubMed  CAS  Google Scholar 

  78. Steele DL, Rajaratnam SM, Redman JR, Ponsford JL. The effect of traumatic brain injury on the timing of sleep. Chronobiol Int 2005;22(1):89–105.

    Article  PubMed  CAS  Google Scholar 

  79. Lewy AJ, Sack RL. The dim light melatonin onset as a marker for circadian phase position. Chronobiol Int 1989;6(1):93–102.

    Article  PubMed  CAS  Google Scholar 

  80. Horne JA, Ostberg O. A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms. Int J Chronobiol 1976;4(2):97–110.

    PubMed  CAS  Google Scholar 

  81. Kropyvnytskyy I, Saunders F, Pols M, Zarowski C. Circadian rhythm of temperature in head injury. Brain Inj 2001;15(6): 511–8.

    PubMed  CAS  Google Scholar 

  82. Douglas MR, Winer JB. Guillain-Barré syndrome and its treatment. Expert Rev Neurother 2006;6(10):1569–74.

    Article  PubMed  Google Scholar 

  83. Winer JB. Guillain Barré syndrome. J Clin Pathol: Mol Pathol 2001;54:381–5.

    CAS  Google Scholar 

  84. Schmidt-Degenhard M. Oneiric perception in intensively treated panplegic polyradiculitis patients. Nervenarzt 1986;57:712–8.

    PubMed  CAS  Google Scholar 

  85. Weiss H. Psychological changes in intensive care patients with acute Guillain-Barré syndrome – psychoanalytic aspects of loss of communication and adjustment. Fortschr Neurol Psychiatr 1991;59(4):134–40.

    PubMed  CAS  Google Scholar 

  86. Weiss H, Rastan V, Mullges W, Wagner R, Toyka K. Psychotic symptoms and emotional distress in patients with Guillain-Barré syndrome. Eur Neurol 2002;47(2):74–8.

    Article  PubMed  CAS  Google Scholar 

  87. Cochen V, Arnulf I, Demeret S, et al. Vivid dreams, hallucinations, psychosis and REM sleep in Guillain-Barré syndrome. Brain 2005;128(Pt 11):2535–45.

    Article  PubMed  CAS  Google Scholar 

  88. Guilleminault C, Mondini S. Mononucleosis and chronic daytime sleepiness. A long-term follow-up study. Arch Intern Med 1986;146(7):1333–5.

    Article  PubMed  CAS  Google Scholar 

Download references

Authors
  1. Sheldon Kapen
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Section Psychopharmacology Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3508TB, PoBox 80082, Utrecht, The Netherlands

    Joris C. Verster

  2. Divison of Clinical Pharmacology and Experimental Therapeutics Department of Medicine, College of Physicians and Surgeons of Columbia University, 630 West 168th Street - Rm # BB813, New York, NY 10032, USA

    S. R. Pandi-Perumal

  3. Department of Psychiatry, Kunin-Lunenfeld Applied Research Unit (KLARU), 3560 Bathurst St., Toronto, M6A 2E1, Canada

    David L. Streiner

Rights and permissions

Reprints and permissions

Copyright information

© 2008 Humana Press, Totowa, NJ

About this chapter

Cite this chapter

Kapen, S. (2008). Sleep and Quality of Life in Traumatic Brain Injury and Guillain–Barré Syndrome. In: Verster, J.C., Pandi-Perumal, S.R., Streiner, D.L. (eds) Sleep and Quality of Life in Clinical Medicine. Humana Press. https://doi.org/10.1007/978-1-60327-343-5_17

Download citation

  • DOI: https://doi.org/10.1007/978-1-60327-343-5_17

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-60327-340-4

  • Online ISBN: 978-1-60327-343-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation