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Arthropod-Borne Viral Encephalitis

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National Institute of Allergy and Infectious Diseases, NIH

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Arthropod-borne viruses can be a common cause of sporadic and epidemic encephalitis. These viruses replicate both in vertebrate and nonvertebrate species and include members of many different families, such as Flaviviridae, Bunyaviridae, etc. (1). Typically, these pathogens are transmitted by mosquitoes and ticks; however, there are exceptions like the non-arthropod-borne Arenaviridae, even including—based on morphology—plant viruses [genus Tospovirus in Bunyaviridae http://edis.ifas.ufl.edu/PP134.

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References

  1. Whitley, R. J. and Kimberlin, D. W. (1999) Viral encephalitis, Pediatr. Rev., 20, 192–198.

    Article  PubMed  CAS  Google Scholar 

  2. Porterfield, J. S. (1975) The basis of arbovirus classification, Med. Biol., 53, 400–405.

    PubMed  CAS  Google Scholar 

  3. Mackenzie, J. S., Gubler, D. J., and Petersen, L. R. (2004) Emerging flaviviruses: the spread and resurgence of Japanese encephalitis, West Nile and Dengue viruses, Nat. Med., 10(12), S98–S109.

    Article  PubMed  CAS  Google Scholar 

  4. Lindenbach, B. D. and Rice, C. M. (2001) Flaviviridae: the viruses and their replication. In: Fields Virology, 4th ed. (Knipe, D. M., Howley, P. M., Griffin, D. E., Lamb, R. A., Martin, M. A., Roizman, B., and Strauss, S. E., eds.), Lippincott Williams 8 Wilkins, Philadelphia, pp. 991–1042.

    Google Scholar 

  5. Westaway, E. G. and Blok, K. (1997) Taxonomy and evolutionary relationships of flaviviruses. In: Dengue and Dengue Hemorrhagic Fever (Gubler, D. J. and Kuno, G., eds.), CAB International, London, pp. 147–173.

    Google Scholar 

  6. Marin, M. S., Zanotto, P. M., Gritsun, T. S., and Gould, E. A. (1995) Phylogeny of TYU, SRE, and CFA virus: different evolutionary rates in the genus Flavivirus, Virology, 206, 1133–1139.

    Article  PubMed  CAS  Google Scholar 

  7. Zanotto, P. M., Gould, E. A., Gao, G. F., Harvey, P. H., and Holmes, E. C. (1996) Population dynamics of flaviviruses revealed by molecular phylogenetics, Proc. Natl. Acad. Sci. U.S.A., 93, 548–553.

    Article  PubMed  CAS  Google Scholar 

  8. Kuno, G., Chang, G. J., Tsuchiya, K. R., Karabatsos, N., and Cropp, C. B. (1998) Phylogeny of the genus Flavivirus, J. Virol., 72, 73–83.

    CAS  Google Scholar 

  9. Billoir, F., de Chesse, R., Tolou, H., de Micco, P., Gould, E. A., and de Lamballerie, X. (2000) Phylogeny of the genus Flavivirus using complete coding sequences of arthropod-borne viruses and viruses with no known vector, J. Gen. Virol., 81, 781–790.

    PubMed  CAS  Google Scholar 

  10. Gould, E. A., de Lamballier, X., Zanotto, P. M. A., and Holmes, E. C. (2001) Evolution, epidemiology, and dispersal of flaviviruses revealed by molecular phylogenies, Adv. Virus Res., 57, 71–103.

    Article  PubMed  CAS  Google Scholar 

  11. Gould, E. A., de Lamballier, X., Zanotto, P. M. A., and Holmes, E. C. (2003) Origins, evolution, and vector/host coadaptations within the genus Flavivirus, Adv. Virus Res., 59, 277–314.

    Article  CAS  Google Scholar 

  12. Gould, E. A., Moss, S. R., and Turner, S. L. (2004) Evolution and dispersal of encephalitic flaviviruses, Arch. Virol. Suppl., 18, 65–84.

    PubMed  Google Scholar 

  13. Gould, E. A. (2002) Evolution of Japanese encephalitis serocomplex viruses, Curr. Top. Microbiol. Immunol., 267, 391–404.

    PubMed  CAS  Google Scholar 

  14. Gritsun, T. S., Lashkevich, V. A., and Gould, E. A. (2003) Tick-borne encephalitis, Antiviral Res., 57, 129–146.

    Article  PubMed  CAS  Google Scholar 

  15. Gubler, D. J. (1997) Dengue and dengue haemorrhagic fever: its history and resurgence as a global public health problem. In: Dengue and Dengue Hemorrhagic Fever (Gubler, D. J. and Kuno, G., eds.), CAB International, London, pp. 1–22.

    Google Scholar 

  16. Gubler, D. J. (2002) The global emergence/resurgence of arboviral diseases as public health problems, Arch. Med. Res., 33, 330–342.

    Article  PubMed  Google Scholar 

  17. Mackenzie, J. S., Barrett, A. D. T., and Deubel, V. (2002) The Japanese encephalitis serological group of Flaviviruses: a brief introduction to the group, Curr. Top. Microbiol., 267, 1–10.

    CAS  Google Scholar 

  18. Solomon, T. (2006) Control of Japanese encephalitis – within our grasp? N. Engl. J. Med., 355(9), 869–871.

    Article  PubMed  CAS  Google Scholar 

  19. Solomon, T. and Vaughn, D. W. (2002) Pathogenesis and clinical features of Japanese encephalitis and West Nile virus infections, Curr. Top. Microbiol. Immunol., 267, 171–194.

    PubMed  CAS  Google Scholar 

  20. Solomon, T. and Winter, P. M. (2004) Neurovirulence and host factors in flavivirus encephalitis – evidence from clinical epidemiology, Arch. Virol. Suppl., 18, 161–170.

    PubMed  Google Scholar 

  21. Solomon, T., Kneen, R., Dung, N. M., Khanh, V. C., Thuy, T. T., Ha, D. Q., Day, N. P., Nisalak, A., Vaughn, D. W., and White, N. J. (1998) Poliomyelitis-like illness due to Japanese encephalitis virus, Lancet, 351, 1094–1097.

    Article  PubMed  CAS  Google Scholar 

  22. Burke, D. S., Lorsomrudee, W., Leake, C. J., Hoke, C. H., Nisalak, A., Chongsvasdi, V., and Laurakpongse, T. (1985) Fatal outcome in Japanese encephalitis, Am. J. Trop. Med. Hyg., 34(6), 1203–1210.

    PubMed  CAS  Google Scholar 

  23. Kienzle, N. and Boyes, L. (2003) Murray Valley encephalitis: case report and review of neurological features, Australas. Radiol., 47, 61–63.

    Article  PubMed  CAS  Google Scholar 

  24. Burrow, J. N., Whelan, P. I., Kilburn, C. J., Fisher, D. A., Currie, B. J., and Smith, D. W. (1998) Australian encephalitis in the Northern territory: clinical and epidemiological features, Aust. NZ J. Med., 28, 590–596.

    CAS  Google Scholar 

  25. Russell, R. C. and Dwyer, D. E. (2000) Arboviruses associated with human disease in Australia, Microbes Infect., 2, 1693–1704.

    Article  PubMed  CAS  Google Scholar 

  26. Marshall, I. D. (1998) Murray Valley and Kunjin encephalitis. In: The Arboviruses: Epidemiology and Ecology (Monath, T. P., ed.), CRC Press, Boca Raton, FL, pp. 151–190.

    Google Scholar 

  27. Mackenzie, J. S., Smith, D. W., Broom, A. K., and Bucens, M. R. (1993) Australian encephalitis in Western Australia, 1978–1991, Med. J. Aust., 158, 591–595.

    PubMed  CAS  Google Scholar 

  28. Bennett, N. M. C. K. (1976) Murray Valley encephalitis 1974. Clinical features, Med. J. Aust., 2, 446–450.

    PubMed  CAS  Google Scholar 

  29. Shroyer, D. A. (2004) Saint Louis encephalitis: a Florida problem. A FMELMG337 document from the Entomology and Nematology Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida, Gainesville (http://edis.ifas.ufl.edu)

  30. Monath, T. P. (1990) Flaviviruses. In: Fields Virology, 2nd ed. (Fields, B. N., Knipe, D. M., Chanock, R. M., Hirsch, M. S., Melnick, J. L., Monath, T. P., and Roizman, B., eds.), Raven Press, New York, pp. 763–814.

    Google Scholar 

  31. Santos, C. L., Sallum, M. A., Franco, H. M., Oshiro, F. M., and Rocco, I. M. (2006) Genetic characterization of St. Louis encephalitis virus in Sao Paulo, Brazil, Mem. Inst. Oswaldo Cruz, 101(1), 57–63.

    Article  PubMed  Google Scholar 

  32. Peters, C. J. and Dalrymple, J. M. (1990) Alphaviruses. In: Fields Virology, 2nd ed. (Fields, B. N., Knipe, D. M., Chanock, R. M., Hirsch, M. S., Melnick, J. L., Monath, T. P., and Roizman, B., eds.), Raven Press, New York, pp. 713–761.

    Google Scholar 

  33. Morris, C. D. (1992) Eastern equine encephalitis. An ENY-700-6-1 document and part of the Mosquito Control Handbook cooperatively by the Department of Entomology and Nematology, University of Florida and a number of other institutions. The electronic version of the Mosquito Control Handbook is provided by the Florida Cooperatice Extension Service, Institute of Food and Agricultural Sciences, University of Florida, Gainesville (http://hammock.ifas.ufl.edu).

  34. Hanson, R. P. (1957) An epizootics of equine encephalomyelitis that occurred in Massachusetts in 1831, Am. J. Trop. Med. Hyg., 6, 858–862.

    PubMed  CAS  Google Scholar 

  35. Kissing, R. E., Rubin, H., Chamberlain, R. W., and Eidson, M. E. (1951) Recovery of virus of eastern encephalomyelitis from blood of a purple grackle, Proc. Soc. Exp. Biol. Med., 77, 398–399.

    Google Scholar 

  36. Kissling, R. E., Chamberlain, R. W., Sikes, R. K., and Eidson, M. E. (1954) Studies on the North American arthropod-borne encephalitides: III. Eastern equine encephalitis in wild birds, Am. J. Hyg., 60, 251–265.

    PubMed  CAS  Google Scholar 

  37. Kissling, R. E., Chamberlain, R. W., Nelson, D. B., and Stamm, D. D. (1955) Studies on the North American arthropod-borne encephalitides. VIII. Equine encephalitis studies in Louisiana, Am. J. Hyg., 62, 233–254.

    PubMed  CAS  Google Scholar 

  38. Howitt, B. (1938) Recovery of the virus of equine encephalomyelitis from a brain of a child, Science, 88, 455–456.

    Article  PubMed  CAS  Google Scholar 

  39. Fothergill, L. D., Dingle, J. H., Farber, S., and Connerley, M. L. (1938) Human encephalitis caused by the virus of the eastern variety of equine encephalomyelitis, N. Engl. J. Med., 219, 411.

    Google Scholar 

  40. Monath, T. R. (1979) Arthropod-borne encephalitis in the Americas, Bull. WHO, 158, 513–533.

    Google Scholar 

  41. Shope, R. E., de Andrade, A. H. P., Bensabeth, G., Causey, O. R., and Humphrey, P. S. (1966) The epidemiology of EEE, WEE, SLE and Tralock viruses, with special reference to birds, in a tropical rain forest near Belem, Brazil, Am. J. Epidemiol., 84, 467–477.

    PubMed  CAS  Google Scholar 

  42. Clarke, D. H. (1961) Two nonfatal human infections with virus of eastern encephalitis, Am. J. Trop. Med. Hyg., 10, 67–70.

    PubMed  CAS  Google Scholar 

  43. Deresiewicz, R. L., Thaler, S. J., Hsu, L., and Zamani, A. A. (1997) Clinical and neuroradiographic manifestations of eastern equine encephalitis, N. Engl. J. Med., 336(26), 1867–1874.

    Article  PubMed  CAS  Google Scholar 

  44. Hauser, G. H. (1948) Human equine encephalomyelitis, easter type, in Louisiana, New Orleans Med. Surg., 100, 551–558.

    CAS  Google Scholar 

  45. Ayres, J. C. and Feemster, R. F. (1949) The sequelae of eastern equine encephalomyelitis, N. Engl. J. Med., 240, 960–962.

    Article  PubMed  CAS  Google Scholar 

  46. Chanas, A. C., Johnson, B. K., and Simpson, D. I. H. (1976) Antigenic relationships of alphaviruses by a simple microculture cross-neutralization method, J. Gen. Microbiol., 32, 295–300.

    CAS  Google Scholar 

  47. Karabatsos, N. (1975) Antigenic relationships of group A arboviruses by plaque reduction neutralization testing, Am. J. Trop. Med. Hyg., 24, 527–532.

    PubMed  CAS  Google Scholar 

  48. Trent, D. W. and Grant, J. A. (1980) A comparison of New World alphaviruses in the western equine encephalomyelitis complex by immunochemical and oligonucleotide fingerprint techniques, J. Gen. Virol., 47, 261–282.

    Article  PubMed  CAS  Google Scholar 

  49. Reisen, W. (1993) The Western encephalitis mosquito, Culex tarsalis, Wing Beats, 4(2), 16.

    Google Scholar 

  50. Baker, A. B. (1958) Western equine encephalitis. Clinical features, Neurology, 8, 880–881.

    PubMed  CAS  Google Scholar 

  51. Finley, K. H. (1959) Postencephalitis manifestations of viral encephalitis. In: Viral Encephalitis (Fields, N. S. and Blattner, R. J., eds.), Charles Thomas, Springfield, IL, pp. 69–91.

    Google Scholar 

  52. Weaver, S. C., Ferro, C., Barrera, R., Boshell, J., and Navarro, J.-C. (2004) Venezuelan equine encephalitis, Ann. Rev. Entomol., 49, 141–174.

    Article  CAS  Google Scholar 

  53. Weaver, S. C., Anischenko, M., Bowen, R., Brault, A. C., Estrada-Franco, J. G., Fernandez, Z., Greene, I., Ortiz, D., Paessler, S., and Powers, A. M. (2004) Genetic determinants of Venezuelan equine virus emergence, Arch. Virol. Suppl., 18, 43–64.

    PubMed  Google Scholar 

  54. Beck, C. E. and Wyckoff, R. W. G. (1938) Venezuelan equine encephalomyelitis, Science, 88, 530.

    Article  PubMed  CAS  Google Scholar 

  55. Kubes, V. and Rios, F. A. (1939) The causative agent of infectious encephalomyelitis in Venezuela, Science, 90, 20–21.

    Article  PubMed  CAS  Google Scholar 

  56. Meissner, J. D., Huang, C. Y.-H., Pfeffer, M., and Kinney, R. M. (1999) Sequencing of prototype viruses in the Venezuelan equine encephalitis antigenic complex, Virus Res., 64, 43–59.

    Article  PubMed  CAS  Google Scholar 

  57. Kinney, R. M., Pfeffer, M., Tsuchyia, K. R., Chang, G.-J. J., and Roehrig, J. T. (1998) Nucleotide sequences of the 26S mRNAs of the viruses defining the Venezuelan equine encephalitis antigenic complex, Am. J. Trop. Med. Hyg., 59, 952–964.

    PubMed  CAS  Google Scholar 

  58. Pletnev, S. V., Zhang, W., Mukhopadhyay, S., Fisher, B. R., Hernandez, R., Brown, D. T., Baker, T. S., Rossman, M. G., and Kuhn, R. J. (2001) Locations of carbohydrate sites of alphavirus glycoproteins show E1 forms an eicosahedral scaffold, Cell, 105, 127–136.

    Article  PubMed  CAS  Google Scholar 

  59. Russo, A. T., White, M. A., and Watowich, S. J. (2006) The crystal structure of the Venezuelan equine encephalitis alphavirus nsP2 protease, Structure, 14, 1449–1458.

    Article  PubMed  CAS  Google Scholar 

  60. Brault, A. C., Powers, A. M., Ortiz, D., Estrada-Franco, J. G., Navarro-Lopez, R., and Weaver, S. C. (2004) Venezuelan equine encephalitis emergence: enhanced vector infection from a single amino acid substitution in the envelope protein, Proc. Natl. Acad. Sci. U.S.A., 101(31), 11344–11349.

    Article  PubMed  CAS  Google Scholar 

  61. Walton, T. E., Alvarez, O., Buckwalter, R. M., and Johnson, K. M. (1973) Experimental infection of horses with an attenuated Venezuelan equine encephalitis vaccine (strain TC-83), J. Infect. Dis., 128, 271–282.

    PubMed  CAS  Google Scholar 

  62. Wang, E., Bowen, R. A., Medina, G., Powers, A. M., Kang, W., Chandler, L. M., Shope, R. E., and Weaver, S. C. (2001) Virulence and viremia characteristics of 1992 epizootic subtype IC Venezuelan equine encephalitis viruses and closely related enzootic subtype ID strains, Am. J. Trop. Med. Hyg., 65, 64–69.

    PubMed  CAS  Google Scholar 

  63. Kinney, R. M., Tsuchiya, K. R., Sneider, J. M., and Trent, D. W. (1992) Genetic evidence that epizootic Venezualan equine encephalitis (VEE) viruses may have evolved from enzootic VEE subtype I-D virus, Virology, 191(2), 569–580.

    Article  PubMed  CAS  Google Scholar 

  64. Wang, E., Barrera, R., Boshell, J., Ferro, C., Freier, J. E., Navarro, J. C., Salas, R., Vasquez, C., and Weaver, S. C. (1999) Genetic and phenotypic changes accompanying the emergence of epizootic subtype IC Venezuelan equine encephalitis viruses from an enzootic subtype ID progenitor, J. Virol., 73(5), 4266–4271.

    PubMed  CAS  Google Scholar 

  65. Trent, D. W., Clewley, J. P., France, J. K., and Bishop, D. H. L. (1979) Immunochemical and oligonucleotide fingerprint analyses of Venezuelan equine encephalomyelitis complex viruses, J. Gen. Virol., 43, 365–381.

    Article  PubMed  CAS  Google Scholar 

  66. Kinney, R. M., Chang, G. J., Tsuchiya, K. R., Sneider, J. M., Roehrig, J. T., Woodward, T. M., and Trent, D. W. (1993) Attenuation of Venezuelan equine encephalitis virus strain TC-83 is encoded by the 5′-noncoding region and the E2 envelope glycoprotein, J. Virol., 67(3), 1269–1277.

    PubMed  CAS  Google Scholar 

  67. Avilan Rovira, J. (1972) Discussion. In: Proceedings of the Workshop-Symposium on Venezuelan Encephalitis Virus, Sci. Publ. 243, Pan American Health Organization, Washington, DC, pp. 189–195.

    Google Scholar 

  68. Bowen, G. S., Fashinell, T. R., Dean, P. B., and Gregg, M. G. (1976) Clinical aspects of human Venezuelan equine encephalitis in Texas, Bull. Pan Am. Health Organ., 10, 46–57.

    PubMed  CAS  Google Scholar 

  69. Johnson, K. M. and Marin, D. H. (1974) Venezuelan equine encephalitis, Adv. Vet. Sci. Comp. Med., 18, 79–116.

    PubMed  CAS  Google Scholar 

  70. Dietz, W. H., Jr., Peralta, P. H., and Johnson, K. M. (1979) The clinical cases of human infection with Venezuelan equine encephalomyelitis virus, subtype I-D, Am. J. Trop. Med. Hyg., 28, 329–334.

    PubMed  Google Scholar 

  71. Ehrenkranz, N. J. and Ventura, A. K. (1974) Venezuelan equine encephalitis virus infection in man, Annu. Rev. Med., 25, 9–14.

    Article  PubMed  CAS  Google Scholar 

  72. Walton, T. E. and Grayson, M. A. (1988) Venezuelan equine encephalomyelitis. In: The Arboviruses: Epidemiology and Ecology, vol. IV, (Monath, T. P., ed.), CRC Press, Boca Raton, FL, pp. 204–231.

    Google Scholar 

  73. McKinney, R. M. (1972) Inactivated and live VEE vaccines – a review. In: Proceedings of the Workshop-Symposium on Venezuelan Encephalitis Virus, Sci. Publ. 243, Pan American Health Organization, Washington, DC, pp. 369–389.

    Google Scholar 

  74. Cole, F. E., Jr., May, S. W., and Eddy, G. A. (1974) Inactivated Venezuelan equine encephalomyelitis vaccine prepared from attenuated (TC-83 strain) virus, Appl. Microbiol., 97, 150–153.

    Google Scholar 

  75. Burke, D. S., Ramsburg, H. H., and Edelman, R. (1977) Persistence in humans of antibody to subtypes of Venezuelan equine encephalomyelitis (VEE) virus after immunization with attenuated (TC-83) VEE virus vaccine, J. Infect. Dis., 136, 354–359.

    PubMed  CAS  Google Scholar 

  76. Gonzales-Scarano, F. and Nathanson, N. (1990) Bunyaviruses. In: Fields Virology, 2nd ed. (Fields, B. N., Knipe, D. M., Chanock, R. M., Hirsch, M. S., Melnick, J. L., Monath, T. P., and Roizman, B., eds.), Raven Press, New York, pp. 1195–1228.

    Google Scholar 

  77. Kappus, K. D., Monath, T. P., Kaminski, R. M., and Calisher, C. H. (1983) Reported encephalitis associated with California serogroup virus infections in the United States, 1963–1981, Prog. Clin. Biol. Res., 123, 31–41.

    PubMed  CAS  Google Scholar 

  78. Thompson, W. H., Kalfayan, B., and Anslow, R. O. (1965) Isolation of California encephalitis group virus from a fatal human illness, Am. J. Epidemiol., 81, 245–253.

    PubMed  CAS  Google Scholar 

  79. Rey, J. R. (2006) La Crosse encephalitis. An ENY-672 (IN420) document by the Entomology and Nematology Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida, Gainesville (http://edis.ifas.ufl.edu).

  80. McJunkin, J. E., Khan, R. R., and Tsai, T. F. (1998) California La Crosse encephalitis, Infect. Dis. Clin. North Am., 12, 83–93.

    Article  PubMed  CAS  Google Scholar 

  81. McJunkin, J. E., Khan, R., de los Reyes, E. C., Parsons, D. L., Minnich, L. L., Ashley, R. G., and Tsai, T. F. (1997) Treatment of a severe case of La Crosse encephalitis with intravenous ribavirin following diagnosis by brain biopsy, Pediatrics, 99(2), 261–267.

    Article  PubMed  CAS  Google Scholar 

  82. McJunkin, J. E., de los Reyes, E. C., Irazuzta, J. E., Ceceres, M. J., Khan, R. R., Minnich, L. L., Fu, K. D., Lovett, G. D., Tsai, T., and Thompson, A. (2001) La Crosse encephalitis in children, N. Engl. J. Med., 344, 801–817.

    Article  PubMed  CAS  Google Scholar 

  83. Cassidy, L. F. and Patterson, J. L. (1989) Mechanism of La Crosse virus inhibition by ribavirin, Antimicrob. Agents Chemother., 33, 2009–2011.

    PubMed  CAS  Google Scholar 

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Georgiev, V.S. (2009). Arthropod-Borne Viral Encephalitis. In: Georgiev, V.S. (eds) National Institute of Allergy and Infectious Diseases, NIH. Infectious Disease. Humana Press. https://doi.org/10.1007/978-1-60327-297-1_19

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