Skip to main content

Part of the book series: Infectious Disease ((ID))

  • 1202 Accesses

Streptococcus is a genus of nonmotile (with few exceptions), nonspore-forming, aerobic to facultatively anaerobic bacteria (family Lactobacillaceae) that occur in pairs (diplococci) or short or long chains and that contain Gram-positive, spherical or ovoid cells. The type species is Streptococcus pyogenes. The Streptococcusbacteria are divided into two major groups, A and B. Group A streptococci (GAS) causes a broad spectrum of diseases that range from uncomplicated pharyngitis (“strep throat”) to life-threatening illnesses, including pneumonia, bacteremia, necrotizing fasciitis (soft tissue disease), and streptococcal toxic shock syndrome (multiorgan failures).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. O’Brien, K. L., Beall, B., Barrett, N. L., Ciesak, P. R., Reingold, A., Farley, M. M., Danila, R., Zell, E. R., Facklam, R., Schwartz, A., and Schuchat, A. (2002) Epidemiolgy of invasive group A Streptococcus disease in the United States, 1995–1999, Clin. Infect. Dis., 35(3), 268–276.

    Article  PubMed  Google Scholar 

  2. Centers for Disease Control (2002) Prevention of perinatal GBS disease, Morb. Mortal. Wkly Rep., 51(RR-11), 5.

    Google Scholar 

  3. Schrag, S. J., Zywicki, S., Farley, M. M., Reingold, A. L., Harrison, L. H., Lefkowitz, L. B., Hadler, J. L., Danila, R., Cieslak, P. R., and Schuchat, A. (2000) Group B streptococcal disease in the era of intrapartum antibiotic prophylaxis, N. Engl. J. Med., 342(1), 15–20.

    Article  PubMed  CAS  Google Scholar 

  4. Carapetis, J. R., Steer, A. C., Mulholland, E. K., and Weber, M. (2005) The global burden of group A streptococcal diseases, Lancet Infect. Dis., 5(11), 685–694.

    Article  PubMed  Google Scholar 

  5. Rosini, R., Rinaudo, C. D., Soriani, M., Lauer, P., Mora, M., Maione, D., Taddei, M., Santi, I., Ghezzo, C., Brettoni, C., Buccato, S., Margarit, I., Grandi, G., and Telford, J. L. (2006) Identification of novel genomic island coding for antigenic pilus-like structures in Streptococcus agalactiae, Mol. Microbiol., 61, 126–141.

    Article  CAS  Google Scholar 

  6. Robinson, D. A., Sutcliffe, J. A., Tewodros, W., Manoharan, A., and Bessen, D. E. (2006) Evolution and global dissemination of macrolide-resistant group A streptococci, Antimicrob. Agents Chemother., 50, 2903–2911.

    Article  PubMed  CAS  Google Scholar 

  7. Lin, J., Kaltoft, M. S., Brandao, A. P., Echaniz-Aviles, G., Brandileone, M. C., Hollingshead, S. K., Benjamin, W. H., and Nahm, M. H. (2006) Validation of a multiplex pneumococcal serotyping assay with clinical samples, J. Clin. Microbiol., 44, 383–388.

    Article  PubMed  CAS  Google Scholar 

  8. Blondeau, J. M. (2004) Emerging resistance to vancomycin, rifampin, and fluoroquinolones in Streptococcus pneumoniae. In: Management of Multiple Drug-Resistant Infections (Gillespie, S. H., ed.), Humana Press, Totowa, NJ, pp. 49–78.

    Google Scholar 

  9. Hansman, D. and Bullen, M. (1967) A resistant pneumococcus, Lancet, 2, 264–265.

    Article  Google Scholar 

  10. Appelbaum, P. C., Bhamjee, A., Scragg, J. N., Hallett, A. F., Bowen, A. J., and Cooper, R. C. (1977) Streptococcus pneumoniae resistant to penicillin and chloramphenicol, Lancet, 2, 995–997.

    Article  PubMed  CAS  Google Scholar 

  11. Evans, W. and Hansman, D. (1963) Tetracycline-resistant pneumococcus, Lancet, 1, 451.

    Article  Google Scholar 

  12. Francis, R. S., May, J., and Spicer, C. C. (1964) Influence of daily penicillin, tetracycline, erythromycin and sulphamethoxypyridazine on exacerbations of bronchitis: a report to the research committee of the British Tuberculosis Association, Br. Med. J., 1, 728–732.

    Article  PubMed  CAS  Google Scholar 

  13. Kislak, J. W. (1967) Type 6 pneumococcus resistant to erythromycin and lincomycin, N. Engl. J. Med., 276, 852.

    Article  PubMed  CAS  Google Scholar 

  14. Klugman, K. P. (1990) Pneumococcal resistance to antibiotics, Clin. Microbiol. Rev., 3(2), 171–196.

    PubMed  CAS  Google Scholar 

  15. Asensi, F., Perez-Tamarit, D., Otero, M. C., Gallego, M., Llanes, S., Abadia, C., and Canto, E. (1989) Imipenem-cilastin therapy in a child with meningitis caused by a multiply resistant pneumococcus, Pediatr. Infect. Dis. J., 399, 590–593.

    Google Scholar 

  16. Novak, R., Henriquies, B., Charpentier, E., Normark, S., and Tuomanen, E. (1999) Emergence of vancomycin tolerance in Streptococcus pneumoniae, Nature, 399, 590–593.

    Article  PubMed  CAS  Google Scholar 

  17. Leclercq, R. and Courvalin, P. (1991) Bacterial resistance to macrolide, lincosamide and streptogramin antibiotics by target modification, Antimicrob. Agents Chemother., 35, 1267–1272.

    PubMed  CAS  Google Scholar 

  18. Courvalin, P. and Carlier, C. (1986) Transposable multiple antibiotic resistance in Streptococcus pneumoniae, Mol. Gen. Genet., 205, 291–297.

    Article  PubMed  CAS  Google Scholar 

  19. Fernández Viladrich, P. (2004) Management of meningitis caused by resistant Streptococcus pneumoniae. In: Management of Multiple Drug-Resistant Infections (Gillespie, S. H., ed.), Humana Press, Totowa, NJ, pp. 31–48.

    Google Scholar 

  20. Paris, M., Hickey, S. M., Uscher, M. I., Shelton, S., Olsen, K. D., and McCracken, G. H., Jr. (1994) Effect of dexamethazone on therapy of experimental penicillin- and cephalosporin-resistant pneumococcal meningitis, Antimicrob. Agents Chemother., 38, 1320–1324.

    PubMed  CAS  Google Scholar 

  21. Kaplan, S. L. (2002) Management of pneumococcal meningitis, Pediatr. Infect. Dis. J., 21, 589–591.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Vassil St. Georgiev PhD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Humana Press, a part of Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Georgiev, V.S. (2009). Streptococcus pneumoniae (Pneumococcal) Disease. In: Georgiev, V.S. (eds) National Institute of Allergy and Infectious Diseases, NIH. Infectious Disease. Humana Press. https://doi.org/10.1007/978-1-60327-297-1_11

Download citation

Publish with us

Policies and ethics