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Pediatric Urology for the Primary Care Physician pp 191–202Cite as

Adolescent Varicocele

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Part of the book series: Current Clinical Urology ((CCU))

Abstract

The word varicocele is derived from the Latin word for vein, varix, and the Greek word for mass, kele. This mass of veins is actually a varicose condition of the veins of the pampiniform plexus.

The varicocele as a medical entity and its treatment was described in a book for the very first time by Cornelius Celsus (c. 25 BC–c. 50 AD) in his “De Medicina”: The veins are swollen and twisted over the testicle, which becomes smaller than its fellow in as much as its nutrition has become defective. He already differentiated between three different levels of dilated veins with separate surgical procedures for each.

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References

  1. Skoog SJ, Roberts KP, Goldstein M, Pryor JL. The adolescent varicocele: what’s new with an old problem in young patients? Pediatrics. 1997;100:112.

    Article  CAS  PubMed  Google Scholar 

  2. Dubin L, Amelar RD. Varicocele size and results of varicocelectomy in selected subfertile men with varicocele. Fertil Steril. 1970;21:606–9.

    CAS  PubMed  Google Scholar 

  3. Hirsh AV, Cameron KM, Tyler JP, et al. The Doppler assessment of varicoceles and internal spermatic vein reflux in infertile men. Br J Urol. 1980;52:50–6.

    Article  CAS  PubMed  Google Scholar 

  4. El Sadr AR, Mina A. Anatomical and surgical aspects in the operative management of varicoceles. Urol Cutaneous Rev. 1950;54:257–62.

    Google Scholar 

  5. Graif M, Hauser R, Hirshebein A, et al. Varicocele and the testicular-renal venous route: hemodynamic Doppler sonographic investigation. J Ultrasound Med. 2000;19(9):627–31.

    CAS  PubMed  Google Scholar 

  6. Wishahi MM. Anatomy of the venous drainage of the human testis: testicular vein cast, microdissection and radiographic demonstration. A new anatomical concept. Eur Urol. 1991;20(2):154–60.

    CAS  PubMed  Google Scholar 

  7. Raman J, Walmsley K, Goldstein M. Inheritance of varicocele. Urology. 2005;65:1186–9.

    Article  PubMed  Google Scholar 

  8. Mohammed A, Chinegwundoh F. Testicular varicocele: an overview. Urol Int. 2009;82(4):373–9. Epub 2009 Jun 8.

    Article  PubMed  Google Scholar 

  9. Prabakaran S, Kumanov P, Tomova A, et al. Adolescent varicocele: association with somatometric parameters. Urol Int. 2006;77(2):114–7.

    Article  PubMed  Google Scholar 

  10. Kumanov P, Robeva RN, Tomova A. Adolescent varicocele: who is at risk? Pediatrics. 2008;121(1):e53–7.

    Article  PubMed  Google Scholar 

  11. Tsao CW, Hsu CY, Chou YC, Wu ST, et al. The relationship between varicoceles and obesity in a young adult population. Int J Androl. 2009;32(4):385–90. Epub 2008 Oct 21.

    Article  PubMed  Google Scholar 

  12. Nakamura M, Namiki M, Okuyama A, et al. Optimal temperature for synthesis of DNA, RNA, and protein by human testis in vitro. Arch Androl. 1988;20(1):41–4.

    Article  CAS  PubMed  Google Scholar 

  13. Okuyama A, Koh E, Kondoh N, et al. In vitro temperature sensitivity of DNA, RNA, and protein syntheses throughout puberty in human testis. Arch Androl. 1991;26(1):7–13.

    Article  CAS  PubMed  Google Scholar 

  14. Fujisawa M, Hayashi A, Okada H, et al. Enzymes involved in DNA synthesis in the testes are regulated by temperature in vitro. Eur Urol. 1997;31(2):237–42.

    CAS  PubMed  Google Scholar 

  15. Goldstein M, Eid JF. Elevation of intratesticular and scrotal skin surface temperature in men with varicocele. J Urol. 1989;142(3):743–5.

    CAS  PubMed  Google Scholar 

  16. Salisz JA, Kass EJ, Steinert BW. The significance of elevated scrotal temperature in an adolescent with a varicocele. Adv Exp Med Biol. 1991;286:245–51.

    Article  CAS  PubMed  Google Scholar 

  17. Dahl EV, Herrick JF. A vascular mechanism for maintaining testicular temperature by counter-current exchange. Surg Gynecol Obstet. 1959;108:697–705.

    CAS  PubMed  Google Scholar 

  18. Hienz HA, Voggenthaler J, Weissbach L. Histological findings in testes with varicocele during childhood and their therapeutic consequences. Eur J Pediatr. 1980;133:139–46.

    Article  CAS  PubMed  Google Scholar 

  19. Sikka SC. Oxidative stress and role of antioxidants in normal and abnormal sperm function. Front Biosci. 1996;1:e78–86.

    CAS  PubMed  Google Scholar 

  20. Abd-Elmoaty MA, Saleh R, Sharma R, Agarwal A. Increased levels of oxidants and reduced antioxidants in semen of infertile men with varicocele. Fertil Steril. 2010;94(4):1531–4.

    Article  CAS  PubMed  Google Scholar 

  21. Shiraishi K, Takihara H, Matsuyama H. Elevated scrotal temperature, but not varicocele grade, reflects testicular oxidative stress-mediated apoptosis. World J Urol. 2010;28(3):359–64.

    Article  CAS  PubMed  Google Scholar 

  22. World Health Organization. Laboratory manual for the examination of human semen and sperm-cervical mucus interaction. 4th ed. New York: Cambridge University Press; 1999.

    Google Scholar 

  23. Gorelick JI, Goldstein M. Loss of fertility in men with varicocele. Fertil Steril. 1993;59(3):613–6.

    CAS  PubMed  Google Scholar 

  24. Witt MA, Lipshultz LI. Varicocele: a progressive or static lesion? Urology. 1993;42:541–3.

    Article  CAS  PubMed  Google Scholar 

  25. World Health Organization. The influence of varicocele on parameters of fertility in a large group of men presenting to infertility clinics. Fertil Steril. 1992;57:1289–93.

    Google Scholar 

  26. Mohamad Al-Ali B, Marszalek M, Shamloul R, et al. Clinical parameters and semen analysis in 716 Austrian patients with varicocele. Urology. 2010;75(5):1069–73.

    Article  Google Scholar 

  27. Steckel J, Dicker AP, Goldstein M. Relationship between varicocele size and response to varicocelectomy. J Urol. 1993;149:769–71.

    CAS  PubMed  Google Scholar 

  28. Diamond DA, Zurakowski D, Bauer SB, et al. Relationship of varicocele grade and testicular hypotrophy to semen parameters in adolescents. J Urol. 2007;178(4 Pt 2):1584–8. Epub 2007 Aug 16.

    Article  PubMed  Google Scholar 

  29. Zachmann M, Prader A, Kind HP, et al. Testicular volume during adolescence. Crosssectional and longitudinal studies. Helv Paediatr Acta. 1974;29:61.

    CAS  PubMed  Google Scholar 

  30. Sigman M, Jarow JP. Ipsilateral testicular hypotrophy is associated with decreased sperm counts in infertile men with varicoceles. J Urol. 1997;158:605.

    Article  CAS  PubMed  Google Scholar 

  31. Haans LCF, Laven JSE, Mali WPTM, et al. Testis volumes, semen quality, and hormonal patterns in adolescents with and without a varicocele. Fertil Steril. 1991;56:731.

    CAS  PubMed  Google Scholar 

  32. Laven JSE, Haans LCF, Mali WPTM, et al. Effects of varicocele treatment in adolescents: a randomized study. Fertil Steril. 1992;58:756.

    CAS  PubMed  Google Scholar 

  33. Guarino N, Tadini B, Bianchi M. The adolescent varicocele: the crucial role of hormonal tests in selecting patients with testicular dysfunction. J Pediatr Surg. 2003;38:120.

    Article  PubMed  Google Scholar 

  34. Evers JH, Collins J, Clarke J. Surgery or embolisation for varicoceles in subfertile men. Cochrane Database Syst Rev. 2009;(1):CD000479.

    Google Scholar 

  35. Ficarra V, Cerruto MA, Liguori G, et al. Treatment of varicocele in subfertile men: the Cochrane review—a contrary opinion. Eur Urol. 2006;49(2):258–63. Epub 2006 Jan 4.

    Article  PubMed  Google Scholar 

  36. Marmar JL, Agarwal A, Prabakaran S, et al. Reassessing the value of varicocelectomy as a treatment for male subfertility with a new meta-analysis. Fertil Steril. 2007;88(3):639–48. Epub 2007 Apr 16.

    Article  PubMed  Google Scholar 

  37. Agarwal A, Deepinder F, Cocuzza M, et al. Efficacy of varicocelectomy in improving semen parameters: new meta-analytic approach. Urology. 2007;70:532–8.

    Article  PubMed  Google Scholar 

  38. Jarow JP, Ogle SR, Eskew LA. Seminal improvement following repair of ultrasound detected subclinical varicoceles. J Urol. 1996;155:1287–90.

    Article  CAS  PubMed  Google Scholar 

  39. Cayan S, Akbay E, Bozlu M. The effect of varicocele repair on testicular volume in children and adolescents with varicocele. J Urol. 2002;168(2):731–4.

    Article  PubMed  Google Scholar 

  40. Kubal A, Nagler HM, Zahalsky M, Budak M. The adolescent varicocele: diagnostic and treatment patterns of pediatricians. A public health concern? J Urol. 2004;171(1):411–3.

    Article  PubMed  Google Scholar 

  41. Jarow JP, Sharlip ID, Belker AM, et al. Best practice policies for male infertility. J Urol. 2002;167:2138–44.

    Article  PubMed  Google Scholar 

  42. Marshall WA, Tanner JM. Variations in the pattern of pubertal changes in boys. Arch Dis Child. 1970;45:13.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  43. Cayan S, Akbay E, Bozlu M, et al. The comparison of physical examination, orchidometry, and color Doppler ultrasonography in the diagnosis of pediatric varicocele and the measurement of testicular volume. J Urol. 2001;165(Suppl):148, abstract 606.

    Google Scholar 

  44. Diamond DA, Paltiel HJ, DiCanzio J, et al. Comparative assessment of pediatric testicular volume: orchidometer versus ultrasound. J Urol. 2000;164(part 2):1111.

    Article  CAS  PubMed  Google Scholar 

  45. Walker AR, Kogan BA. Cost-benefit analysis of scrotal ultrasound in treatment of adolescents with varicocele. J Urol. 2010;183(5):2008–11.

    Article  PubMed  Google Scholar 

  46. Practice Committee of American Society for Reproductive Medicine. Report on varicocele and infertility. Fertil Steril. 2008;90(5 Suppl):S247–9.

    Google Scholar 

  47. Mori MM, Bertolla RP, Fraietta R, et al. Does varicocele grade determine extent of alteration to spermatogenesis in adolescents? Fertil Steril. 2008;90(5):1769–73.

    Article  PubMed  Google Scholar 

  48. Cayan S, Shavakhabov S, Kadioğlu A. Treatment of palpable varicocele in infertile men: a meta-analysis to define the best technique. J Androl. 2009;30(1):33–40. Epub 2008 Sep 4.

    Article  PubMed  Google Scholar 

  49. Palomo A. Radical cure of varicocele by a new technique: preliminary report. J Urol. 1949;61:604–7.

    CAS  PubMed  Google Scholar 

  50. Tauber R, Johnsen N. Antegrade scrotal sclerotherapy for the treatment of varicocele: technique and late results. J Urol. 1994;151(2):386–90.

    CAS  PubMed  Google Scholar 

  51. Galfano A, Novara G, Iafrate M, et al. Surgical outcomes after modified antegrade scrotal sclerotherapy: a prospective analysis of 700 consecutive patients with idiopathic varicocele. J Urol. 2008;179(5):1933–7. Epub 2008 Mar 18.

    Article  PubMed  Google Scholar 

  52. Ficarra V, Zanon G, D’Amico A, et al. Percutaneous, laparoscopic, and surgical treatment of idiopathic varicocele: analysis of costs. Arch Ital Urol Androl. 1998;70(2):57–64.

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Urology, University Hospitals Gasthuisberg, Leuven, Belgium

    Thomas Tailly M.D. & Guy Bogaert M.D., Ph.D.

Authors
  1. Thomas Tailly M.D.
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  2. Guy Bogaert M.D., Ph.D.
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Corresponding author

Correspondence to Guy Bogaert M.D., Ph.D. .

Editor information

Editors and Affiliations

  1. Division of Pediatric Urology, Department of Urology, University of Rochester Medical Center, Rochester, New York, USA

    Ronald Rabinowitz

  2. Division of Pediatric Urology, Department of Urology, University of Rochester Medical Center, Rochester, New York, USA

    William C. Hulbert

  3. Chesapeake Urology, Owings Mills, Maryland, USA

    Robert A. Mevorach

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Tailly, T., Bogaert, G. (2014). Adolescent Varicocele. In: Rabinowitz, R., Hulbert, W., Mevorach, R. (eds) Pediatric Urology for the Primary Care Physician. Current Clinical Urology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-60327-243-8_23

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  • DOI: https://doi.org/10.1007/978-1-60327-243-8_23

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-60327-242-1

  • Online ISBN: 978-1-60327-243-8

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