Skip to main content

Future Trends in Antimicrobial Use

  • Chapter
  • First Online:
Management of Antimicrobials in Infectious Diseases

Part of the book series: Infectious Disease ((ID))

  • 1765 Accesses

Abstract

The rapidly expanding challenge of antibiotic resistance impacts patients across the globe. Antibiotic-resistant organisms are becoming a massive clinical challenge in the twenty-first century. As outlined in the preceding chapters, all medical practitioners must be aware of the implications of drug resistance when prescribing therapy, as it is becoming very difficult to eradicate infections caused by these antibiotic-resistant pathogens. Pharmaceutical companies do not have vast new drugs in the pipeline. In many ways, we have come to the point as frightening as the preantibiotic era: For patients with multidrug-resistant bacteria, there is no magic bullet.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 269.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Todd JK, Todd N, Damato J et al. (1984). Bacteriology and treatment of purulent nasopharyngitis: A double blind placebo-controlled evaluation. Pediatr Infect Dis 3:226–232

    Article  PubMed  CAS  Google Scholar 

  2. Stott NCH, West RR (1976). Randomised controlled trial of antibiotics in patients with cough and purulent sputum. BMJ 6035:556–559

    Article  Google Scholar 

  3. Mainous AG, III, Zoorob RJ, Oler MJ et al. (1997). Patient knowledge of colds: Implications for antibiotic expectations and unnecessary utilization. J Family Pract 45:75–83

    Google Scholar 

  4. Mainous AG, III, Hueston WJ, Eberlein C (1997). Colour of respiratory discharges and antibiotic use. Lancet 350:1077

    Article  PubMed  Google Scholar 

  5. Ranji SR, Steinman MA, Shojania KG et al. (2008). Interventions to reduce unnecessary antibiotic prescribing: A systematic review and quantitative analysis. Med Care 46:847–862

    Article  PubMed  Google Scholar 

  6. Roumie CL, Halasa NB, Grijalva CG et al. (2005). Trends in antibiotic prescribing for adults in the United States – 1995 to 2002. J Gen Intern Med 20:697–702

    Article  PubMed  Google Scholar 

  7. Rubin MA, Bateman K, Donnelly S et al. (2006). Use of a personal digital assistant for managing antibiotic prescribing for outpatient respiratory tract infections in rural communities. J Am Med Inform Assoc 13:627–634

    Article  PubMed  Google Scholar 

  8. National Vaccine Advisory Committee (1999). Lessons learned from a review of the development of selected vaccines. Pediatrics 104:942–950

    Article  Google Scholar 

  9. MMWR (1998). Progress toward eliminating Haemophilus influenzae type b disease among infants and children – United States, 1987–1997. MMWR Morb Mortal Wkly Rep 47(46):993–998

    Google Scholar 

  10. De Wals P, Erickson L, Poirier B et al. (2009). How to compare the efficacy of conjugate vaccines to prevent acute otitis media?. Vaccine 27:2877–2883

    Article  PubMed  Google Scholar 

  11. Georgousakis MM, McMillan DJ, Batzloff MR et al. (2009). Moving forward: A mucosal vaccine against group A streptococcus. Expert Rev Vaccines 8:747–760

    Article  PubMed  CAS  Google Scholar 

  12. Arias CA, Murray BE (2009). Antibiotic-resistant bugs in the twenty-first century – A clinical super-challenge. N Engl J Med 360:439–443

    Article  PubMed  CAS  Google Scholar 

  13. Brown EL, Dumitrescu O, Thomas D et al. (2009). The Panton-Valentine leukocidin vaccine protects mice against lung and skin infections caused by Staphylococcus aureus USA300. Clin Microbiol Infect 15:156–164

    Article  CAS  Google Scholar 

  14. Poole K (2003). Overcoming multidrug resistance in gram-negative bacteria. Current Opinion in Investigational. Drugs 4:128–139

    CAS  Google Scholar 

  15. Glaser R, Rabin B, Chesney M et al. (1999). Stress induced immunomodulation: Implications for infectious diseases? J Am Med Assoc 281:2268–2270

    Article  CAS  Google Scholar 

  16. Grant A, Gothard P, Thwaites G (2008). Managing drug resistant tuberculosis. BMJ 337:a1110

    Article  PubMed  Google Scholar 

  17. Devaux I, Kremer K, Heersma H et al. (2009). Clusters of multidrug-resistant mycobacterium tuberculosis cases, Europe. Emerg Infect Dis 15:1052–1060

    Article  PubMed  Google Scholar 

  18. Grigoryan L, Haaijer-Ruskamp FM, Burgerhof JGM et al. (2006). Self-medication with antimicrobial drugs in Europe. Emerg Infect Dis 12:452–459

    PubMed  Google Scholar 

  19. Drug Utilization Group, Latin America (1997). Multi-center study on self-medication and self-prescription in six Latin American countries. Clin Pharmacol Ther 61:488–493

    Article  Google Scholar 

  20. Hui L, LI XS, Zeng XJ, Dai YH et al. (1997). Patterns and determinants of use of antibiotics for acute respiratory tract infection in children in China. Pediatr Infectious Dis J 16:560–564

    Article  CAS  Google Scholar 

  21. Lansang MA, Lucas-Aquino R, Tupasi TE et al. (1990). Purchase of antibiotics without a prescription in Manila, The Philippines. Inappropriate choices and doses. J Clin Epidemiol 43:61–67

    Article  PubMed  CAS  Google Scholar 

  22. Hossain MM, Glass RI, Khan MR (1982). Antibiotic use in a rural community in Bangladesh. Int J Epidemiol 11:402–405

    Article  PubMed  CAS  Google Scholar 

  23. Casner PR, Guerra LG (1992). Purchasing prescription medication in Mexico without a prescription: The experience at the border. West J Med 156:512–516

    PubMed  CAS  Google Scholar 

  24. Mainous AGIII, Cheng AY, Garr RC et al. (2005). Nonprescribed antimicrobial drugs in Latino Community, South Carolina. Emerg Infect Dis 11:883–888

    PubMed  Google Scholar 

  25. Mainous AGIII, Diaz VA, Carnemolla M (2008). Factors affecting Latino adults’ use of antibiotics for self-medication. J Am Board Fam Med 21:128–134

    Article  PubMed  Google Scholar 

  26. Mainous AGIII, Everett CJ, Post RE et al. (2009). Availability of antibiotics for purchase without a prescription on the Internet. Ann Fam Med 7(5):431–435

    Google Scholar 

  27. Gilbert P, McBain AJ (2003). Potential impact of increased use of biocides in consumer products on prevalence of antibiotic resistance. Clin Microbiol Rev 16:189–208

    Article  PubMed  CAS  Google Scholar 

  28. Aiello AE, Larson E (2003). Antibacterial cleaning and hygiene products as an emerging risk factor for antibiotic resistance in the community. Lancet Infect Dis 3:501–506

    Article  PubMed  Google Scholar 

  29. Brooks SE, Walczak MA, Hameed R et al. (2002). Chlorhexidine resistance in antibiotic-resistant bacteria isolated from the surfaces of dispensers of soap containing chlorhexidine. Infect Control Hosp Epidemiol 23:692–695

    Article  PubMed  Google Scholar 

  30. Aiello AE, Marshall B, Levy SB (2005). Antibacterial cleaning products and drug resistance. Emerg Infect Dis 11:1565–1570

    PubMed  Google Scholar 

  31. Tan L, Nielsen NH, Young DC et al. (2002). Use of antimicrobial agents in consumer products. Arch Dermatol 138:1082–1086

    Article  PubMed  Google Scholar 

  32. Wegener HC, Aarestrup FM, Jensen LB et al. (1999). Use of antimicrobial growth promoters in food animals and Enterococcus faecium resistance to therapeutic antimicrobial drugs in Europe. Emerg Infect Dis 5:329–335

    Article  PubMed  CAS  Google Scholar 

  33. Sato K, Bartlett PC, Saeed MA (2005). Antimicrobial susceptibility of Escherichia coli isolates from dairy farms using organic vs conventional production methods. J Am Vet Med Assoc 226:589–594

    Article  PubMed  CAS  Google Scholar 

  34. McDonald CL, Kuehnert MJ, Tenover FC et al. (1997). Vancomycin-resistant enterococci outside the health care setting: Prevalence, sources, and public health. Emerg Infect Dis 3:311–317

    Article  PubMed  CAS  Google Scholar 

  35. Silbergeld EK, Graham J, Price LB (2008). Industrial food production, antimicrobial resistance, and human health. Annu Rev Public Health 29:151–169

    Article  PubMed  Google Scholar 

  36. Islam M, Doyle MP, Phatak SC et al. (2004). Persistence of enterohemorrhagic Escherichia coli O157:H7 in soil and on leaf lettuce and parsley grown in fields treated with contaminated manure composts or irrigation water. J Food Prot 67:1365–1370

    PubMed  Google Scholar 

  37. World Health Organization (1997). The medical impact of the use of antimicrobials in food animals. Report from a WHO meeting; Berlin, Germany 1997 Oct 13–17. Geneva:World Health Organization

    Google Scholar 

  38. Commission regulation of amending council directive 70/524/EEC concerning additives in feedingstuffs as regards withdrawal of the authorisation of certain antibiotics (1998). Document No.:VI/7767/98. European Commission, Brussels, Belgium

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Arch G. Mainous III .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Mainous, A.G. (2010). Future Trends in Antimicrobial Use. In: Mainous III, A., Pomeroy, C. (eds) Management of Antimicrobials in Infectious Diseases. Infectious Disease. Humana Press. https://doi.org/10.1007/978-1-60327-239-1_20

Download citation

  • DOI: https://doi.org/10.1007/978-1-60327-239-1_20

  • Published:

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-60327-238-4

  • Online ISBN: 978-1-60327-239-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics