Treatment of Advanced and Recurrent Carcinoma
Progestins were the first drugs to be used in systemic therapy of endometrial cancer. After four decades of clinical trials, their role has been narrowed to a relatively small percentage of tumors that have metastasized but are well differentiated and rich in hormonal receptors. Nevertheless, with better selection of patients likely to benefit from hormonal therapy and the exploration of potential role after chemotherapy, one may look forward to new directions of interest.
KeywordsEndometrial cancer Progestins Hormone receptors
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