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Proteomic Methods in Cancer Research

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Bioinformatics in Cancer and Cancer Therapy

Part of the book series: Cancer Drug Discovery and Development ((CDD&D))

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Abstract

Recent advancements and progress in proteomics technologies and research protocols have made a demonstrable impact upon clinical investigations, particularly in the area of cancer research. This chapter reviews the overall requirements and approaches involved in clinical proteomics research with particular emphasis on and review of accomplishments in the field of cancer research and therapy. A detailed discussion of the challenges in clinical proteomic research is presented along with a valuable review of protein purification and protein analytical platforms. Extensive discussion on the use of various clinical proteomic mass spectrometric approaches is provided.

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Authors and Affiliations

  1. GenNext Technologies™, Inc., Montara, CA, USA

    Scot Weinberger & Egisto Boschetti

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  1. Scot Weinberger
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  2. Egisto Boschetti
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Correspondence to Scot Weinberger .

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  1. Division of Thoracic Surgery, Brigham & Women's Hospital, Longwood Ave. 221, Boston, 02115, U.S.A.

    Gavin J. Gordon

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© 2009 Humana Press, a part of Springer Science+Business Media, LLC

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Weinberger, S., Boschetti, E. (2009). Proteomic Methods in Cancer Research. In: Gordon, G. (eds) Bioinformatics in Cancer and Cancer Therapy. Cancer Drug Discovery and Development. Humana Press. https://doi.org/10.1007/978-1-59745-576-3_6

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