Abstract
Microbial risk assessment (MRA) is used to evaluate foodborne hazards, the likelihood of exposure to those hazards, and the resulting public-health impact. It is generally recognized to consist of four parts: hazard identification, hazard characterization, exposure assessment, and risk characterization. Model predictions generated by MRAs are most often expressed as the estimated likelihood of foodborne illness and/or number of deaths in a given population for a given period. MRA is used increasingly to inform decision-making aimed both at managing human health risks from foodborne pathogens and at devising standards for promoting safe and fair international food trade. This chapter discusses how MRA fits into the larger context of risk analysis, describes in detail the process of MRA, reviews examples of recently completed MRAs, and suggests steps towards further improvement of the MRA process.
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References
Rodricks, J. V. (1992) Calculated Risks: The Toxicity and Human Health Risks of Chemicals in Our Environment. Cambridge University Press, Cambridge, UK.
Rodricks, J. V. (2003) What happened to the Red Book's second most important recommendation? Human Ecol. Risk Assess. 9, 1169–1180.
Press, F. (1983) Letter from the Chairman, pp. iii–iv. In (National Research Council) Risk Assessment in the Federal Government: Managing the Process. Committee on the Institutional Means for Assessment of Risks to Public Health, Commission on Life Sciences, National Academy Press, Washington, DC, 191 pp.
National Research Council. (1983) Risk Assessment in the Federal Government: Managing the Process. Committee on the Institutional Means for Assessment of Risks to Public Health, Commission on Life Sciences, National Academy Press, Washington, DC, 191 pp.
Forsythe, S.J. (2002) The Microbiological Risk Assessment of Food. Blackwell, Oxford, UK.
Food and Agricultural Organization of the United Nations. (1999) Principles and guidelines for the conduct of microbiol risk assessment. In Codex Alimentairus Food Hygiene Basic Texts, 2nd edition, pp. 53–62. FAO, Rome.
Food and Agricultural Organization of the United Nations. (2000) Report of the Joint FAO/WHO expert consultation on risk assessment of microbiological hazards in foods. FAO Headquarters, Rome, 17-21 July 2000. FAO Food and Nutrition Paper, 71.
Committee on Risk Perception and Communication, NRC. (1989) Improving Risk Communication, The National Academies Press, Washington, DC.
Vose, D. (2000) Risk Analysis: A Quantitative Guide, John Wiley & Sons, Chichester, UK.
Wachsmuth, K., Kause, J., Maczka, C., Ebel, E., Schlosser, E., and Anderson, S. (2003) Microbial Risk Assessment as a Tool for Guiding Food Safety. Marcel Dekker, New York.
National Advisory Committee on Microbiological Criteria for Foods (NACMCF). (1998) Principles of risk assessment for illness caused by foodborne biological agents. J. Food Prot. 61, 1071–107
Lammerding, A. M. and Paoli, G. M. (1997) Quantitative risk assessment: an emerging tool for emerging foodborne pathogens. Emerg. Infect. Dis. 3, 483–487.
Kasuga, F., Hirota, M., Wada, M., et al. (2006) Outbreak data for Salmonella dose response. Proceedings of the First International Conference on Microbial Risk Assessment, College Park, MD. J. Food Prot. (In press).
Food and Drug Administration. (2001) Public health impact of Vibrio parahaemolyticus in raw molluscan shellfish. Available at http://vm.cfsan.fda.gov/~dms/vprisk.html (accessed on 1/8/07).
Buchanan, R. L., Damert, W. G., Whiting, R. C., and van Schothorst, M. (1997) Use of epidemiologic and food survey data to estimate a purposefully conservative dose-response relationship for Listeria monocytogenes levels and incidence of listeriosis. J. Food Prot. 60, 918–922.
HHS/USDA. (2003) Quantitative assessment of relative risk to public health from food-borne Listeria monocytogenes among selected categories of ready-to-eat foods. Available at http://www.foodsafety.gov/~dms/lmr2-toc.html (accessed on 1/8/07).
Dennis, S. B., Miliotis, M. D., and Buchanan, R. L. (2002) Hazard characterization/ dose-response assessment. In: Microbial Risk Assessment in Food Processing (Brown, M. and Stringer, M., eds.), Woodhead, Cambridge, UK, pp. 83–86.
Levine, M. M., Black, R. E., Clements, M. L., Nalin, D. R., Cisneros, L., and Finkelstein, R. A. (1981) Volunteer studies in development of vaccines against cholera and enterotoxigenic Escherichia coli: a review. In Acute Enteric Infections in Children: New Prospects for Treatment and Prevention (Holme, T., Holmgren, J., Merson, M. H., and Molby, R., eds.), Elsevier/North-Holland, Amsterdam, pp. 443–459.
Sprong, R. C., Hulstein, M. F., and Van der Meer, R. (1999) High intake of milk fat inhibits intestinal colonization of Listeria but not of Salmonella in rats. J. Nutr. 129, 1382–1389.
Coleman, M. and Marks, H. (1998) Topics in dose-response modeling. J. Food Prot. 61, 1550–1559.
President's Council on Food Safety. (1999) Egg safety from production to consumption: an action plan to eliminate Salmonella Enteritidis illnesses due to eggs. Partnership of the US Department of Agriculture, Department of Health and Human Services, Environmental Protection Agency and the Department of Commerce, Washington, DC.
Committee on the Review of the USDA E. coli O157:H7 Farm-to-Table Process Risk Assessment. (2002) Escherichia coli O157:H7 in Ground Beef: Review of a Draft Risk Assessment. The National Academies Press, Washington, DC.
Food Safety and Inspection Service. (2000) Draft Risk Assessment of the Public Health Impact of Escherichia coli O157:H7 in Ground Beef. The US Department of Agriculture, Washington, DC.
Notermans, S., Dufrenne, J., Teunis, P., Beumer, R., Te Giffel, M., and Peeters Weem, P. (1997) A risk assessment study of Bacillus cereus present in pasteurized milk. Food Microbiol. 14, 143–151.
FAO/WHO. (2001) Hazard identification, exposure assessment and hazard characterization of Campylobacter spp. in broiler chickens and Vibrio spp. in seafood—Joint FAO, Rome/ WHO Expert Consultation, Geneva, Switzerland, 23–27 July, 2001.
Rosenquist, H., Nielsen, N. L., Sommer, H. M., Norrung, B., and Christensen, B. B. (2003) Quantitative risk assessment of human campylobacteriosis associated with thermophilic Campylobacter species in chickens. Int. J. Food Microbiol. 83, 87–103.
Center for Veterinary Medicine, Rockville, Maryland, US Food and Drug Administration. (2001) Risk Assessment on the Human Health Impact of Fluoroquinolone Resistant Campylobacter Associated with the Consumption of Chicken.
Cassin, M. H., Lammerding, A. M., Todd, E. C., Ross, W., and McColl, R. S. (1998) Quantitative risk assessment for Escherichia coli O157:H7 in ground beef hamburgers. Int. J. Food Microbiol. 41, 21–44.
Netherlands National Institute of Public Health and the Environment. (2001) Risk assessment of Shiga-toxin producing Escherichia coli O157 in steak tartare in the Netherlands. RIVM, Bilthoven. Report 257851003.
Gallagher, D. L., Ebel, E. D., and Kause, J. R. (2003) FSIS risk assessment for Listeria monocytogenes in deli meats. Food Safety and Inspection Service, US Department of Agriculture, Washington, DC.
Bemrah, N., Sanaa, M., Cassin, M. H., Griffiths, M. W., and Cerf, O. (1998) Quantitative risk assessment of human listeriosis from consumption of soft cheese made from raw milk. Prev. Vet. Med. 37, 129–145.
Whiting, R. C. and Buchanan, R. L. (1997) Development of a quantitative risk assessment model for Salmonella enteritidis in pasteurized liquid eggs. Int. J. Food Microbiol. 36, 111–125.
Alban, L., Olsen, A. M., Nielsen, B., Sorensen, R., and Jessen, B. (2002) Qualitative and quantitative risk assessment for human salmonellosis due to multi-resistant Salmonella Typhimurium DT104 from consumption of Danish dry-cured pork sausages. Prev. Vet. Med. 52, 251–265.
Lindqvist, R., Sylven, S., and Vagsholm, I. (2002) Quantitative microbial risk assessment exemplified by Staphylococcus aureus in unripened cheese made from raw milk. Int. J. Food Microbiol. 78, 155–170.
Schroeder, C. M., Latimer, H. K., Schlosser, W. D., et al. (2006) Overview and summary of the Food Safety and Inspection Service risk assessment for Salmonella Enteritidis in shell eggs, October 2005. Foodborne Pathogens and Diease. 3, 403–412.
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Schroeder, C.M., Jensen, E., Miliotis, M.D., Dennis, S.B., Morgan, K.M. (2007). Microbial Risk Assessment. In: Simjee, S. (eds) Foodborne Diseases. Infectious Disease. Humana Press. https://doi.org/10.1007/978-1-59745-501-5_18
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DOI: https://doi.org/10.1007/978-1-59745-501-5_18
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