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Premature Thelarche

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When Puberty is Precocious

Part of the book series: Contemporary Endocrinology ((COE))

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Abstract

Premature thelache is the development of breast tissue prior to the normal age of pubertal onset. it can arise as a result of a number of different etiologies. This chapter provides an overview both of the physiology of normal breast development and of the causes of early thelarche, including benign self-limited premature thelarche, gonadotropin-independent precocious puberty, gonadotropin-dependent precocious puberty, exposure to exogenous estrogens, and non-hormonal mechanisms. A careful history and physical examination is essential is essential in order to determine the proper diagnostic approach. it is important for the clinican to differentiate benign premature thelarche from other causes that can have deleterious consequences, such as true precocious puberty.

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Authors
  1. Linda A. DiMeglio MD, MPH
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  2. Adda Grimberg MD
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Editors and Affiliations

  1. Departments of Pediatrics and Cellular and Integrative Physiology, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN

    Ora H. Pescovitz MD

  2. Section of Pediatric Endocrinology and Diabetology, Department of Pediatrics, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN, USA

    Emily C. Walvoord MD

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DiMeglio, L.A., Grimberg, A. (2007). Premature Thelarche. In: Pescovitz, O.H., Walvoord, E.C. (eds) When Puberty is Precocious. Contemporary Endocrinology. Humana Press. https://doi.org/10.1007/978-1-59745-499-5_8

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  • DOI: https://doi.org/10.1007/978-1-59745-499-5_8

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