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Selection of Cord Blood Unit(s) for Transplantation

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Allogeneic Stem Cell Transplantation

Part of the book series: Contemporary Hematology ((CH))

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Abstract

Over the past decade, cord blood (CB) has been established as an alternative source of donor cells for allogeneic hematopoietic stem cell transplantation. The outcome of CB transplants, particularly in children, is similar to the unrelated donor transplants using bone marrow cell or mobilized peripheral blood progenitor cells [1-4]. Early experience in adult CB transplantation was hampered by poor engraftment and immune recovery [5-7]. Recent experiences with better risk patients, double CB unit transplants, and submyeloablative preparative regimens have been more encouraging [8-10].

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Author information

Authors and Affiliations

  1. Cancer Care Manitoba, Winnipeg, MB, Canada

    Donna A. Wall

  2. Pediatric Blood and Marrow Transplantation Program, Texas Transplant Institute, San Antonio, TX, USA

    Ka Wah Chan

Authors
  1. Donna A. Wall
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  2. Ka Wah Chan
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Editors and Affiliations

  1. University Hospitals Case Medical Center, Cleveland, OH, USA

    Hillard M. Lazarus

  2. Case Western Reserve University, Cleveland, OH, USA

    Mary J. Laughlin

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Wall, D.A., Chan, K.W. (2010). Selection of Cord Blood Unit(s) for Transplantation. In: Lazarus, H.M., Laughlin, M.J. (eds) Allogeneic Stem Cell Transplantation. Contemporary Hematology. Humana Press. https://doi.org/10.1007/978-1-59745-478-0_21

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  • DOI: https://doi.org/10.1007/978-1-59745-478-0_21

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-934115-33-6

  • Online ISBN: 978-1-59745-478-0

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