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Chronic Prostatitis/Chronic Pelvic Pain Syndrome pp 111–123Cite as

Neuromuscular and Psychoactive Treatments for Chronic Prostatitis

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Part of the book series: Current Clinical Urology ((CCU))

Summary

Once the traditional first-line therapies for chronic prostatitis/chronic pelvic pain Syndrome (CP/CPPS) consisting of antibiotics, alpha-blockers, and anti-inflammatory medications fail, there are several other treatments to consider. One of the findings in men with CP/CPPS is alterations in the nervous system that are found in other chronic pain syndromes and result in hyperexcitability of the central nervous system and neuropathic pain. Medications used to treat such pain include tricyclic and nontricyclic antidepressants and anticonvulsants. These men are also found to have increased tone in the muscles of the pelvic floor and external urethral sphincter. Medications used to treat this spasticity include those used in back pain with spasm, such as cyclobenzaprine and Tizanidine. Medications such as montelukast, which is used to treat interstitial cystitis, may also be useful in men with CP/CPPS. Finally, surgical procedures such as bladder neck incision or interStim implantation may also have a role in the treatment of these patients.

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  1. Temple University School of Medicine, Philadelphia, PA

    Michel Pontari

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  1. Cleveland Clinic, Glickman Urological and Kidney Institute, Cleveland, Ohio

    Daniel A. Shoskes MD

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Pontari, M. (2008). Neuromuscular and Psychoactive Treatments for Chronic Prostatitis. In: Shoskes, D.A. (eds) Chronic Prostatitis/Chronic Pelvic Pain Syndrome. Current Clinical Urology. Humana Press. https://doi.org/10.1007/978-1-59745-472-8_9

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  • DOI: https://doi.org/10.1007/978-1-59745-472-8_9

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