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Peripheral Effects of Iron Deficiency

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Iron Deficiency and Overload

Part of the book series: Nutrition and Health ((NH))

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Summary

• Clinical manifestations of iron deficiency were described since 1500 bc and were well known in 16th and 17th century Europe as part of the disease “chlorosis”.

• The major cause of iron deficiency is blood loss, commonly from the gastro-intestinal tract in adults.

• The hematologic changes characteristic of iron deficiency include hypochromic and microcytic anemia.

• The tongue and mouth, hypopharynx and esophagus, stomach, nails, and hair are common epithelial tissues affected by iron deficiency.

• Glossitis, cheilitis, koilonychia, dysphagia, and pica are the signs and symptoms commonly associated with iron deficiency and iron deficiency anemia.

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  1. Division of Hematology/Oncology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA

    Daniel B. Costa MD & Reed E. Drews MD

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  1. Dept. Psychology, Bar-Ilan University, Ramat Gan, 52900, Israel

    Shlomo Yehuda

  2. Dept. Psychology, Boston University, Cummington St. 64, Boston, 02215-2407, USA

    David I. Mostofsky

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Costa, D.B., Drews, R.E. (2009). Peripheral Effects of Iron Deficiency. In: Yehuda, S., Mostofsky, D. (eds) Iron Deficiency and Overload. Nutrition and Health. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59745-462-9_9

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