Abstract
Differences between HIV-1 genetic clades on pathogenicity, transmissibility, and other biological features often have been difficult to prove, due to multiple factors, including large intrasubtype diversity, frequent recombination, and methodological issues. In spite of the difficulties and limitations of the studies, evidence of some associations of HIV-1 clades with biological features has been found
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References
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Thomson, M.M. (2009). HIV-1 Genetic Diversity and Its Biological Significance. In: Paul, R., Sacktor, N., Valcour, V., Tashima, K. (eds) HIV and the Brain. Current Clinical Neurology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59745-434-6_13
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