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Gastrointestinal Syndromes Due to Diabetes Mellitus

  • Chapter
Book cover Diabetic Neuropathy

Part of the book series: Clinical Diabetes ((CLD))

Abstract

Diabetes mellitus is a condition that might result in a variety of derangements of gastrointestinal (GI) structure and function. Disturbances may manifest as symptoms and metabolic changes that in turn, might impich in the management of the patient with diabetes. The present chapter describes the pathophysiology, clinical findings, and management options dealing with the main clinical syndromes associated with disturbances of GI physiology in diabetics. It deals with esophageal dysfunction, sometimes subclinical, but often a source of bothersome upper GI symptoms and also, describes the gastroparesis syndrome, arguably the most characteristic form of gastroduodenal dysfunction in the diabetic. It deals as well with the complex issue of diarrhea in the diabetic patient, often multifactorial and sometimes resulting from a mixture of pathophysiological abnormalities related to diabetic sequela and association with common GI ailments, such as irritable bowel syndrome. Similarly, some space is dedicated to the issue of constipation and fecal incontinence in the patient with diabetes, a particularly troublesome problem quite common in long-standing diabetics. The chapter also provides advice about indications and interpretation of various diagnostic test and reviews the main drugs now available or expected in the future for dealing with these various clinical problems.

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Authors and Affiliations

  1. Digestive System Research Unit, Hospital General Vall d’Hebron, Autonomous University of Barcelona, Barcelona, Spain

    Juan-R. Malagelada MD

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  1. Juan-R. Malagelada MD
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Editors and Affiliations

  1. Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA

    Aristidis Veves MD, DSc

  2. Manchester Royal Infirmary and University of Manchester, Manchester, UK

    Rayaz A. Malik MBChB, PhD

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Malagelada, JR. (2007). Gastrointestinal Syndromes Due to Diabetes Mellitus. In: Veves, A., Malik, R.A. (eds) Diabetic Neuropathy. Clinical Diabetes. Humana Press. https://doi.org/10.1007/978-1-59745-311-0_26

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  • DOI: https://doi.org/10.1007/978-1-59745-311-0_26

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