Basic Neurophysiology and the Cortical Basis of EEG

  • Gregory L. Holmes
  • Roustem Khazipov


Clinical neurophysiological studies are based on the recording of both spontaneous electrical activity, as with the EEG, or with stimulated responses, such as evoked potentials. The electrical signaling within these neuronal circuits is responsible for both the spontaneous and evoked electrical activity that is routinely measured in the clinical neurophysiology laboratory. This chapter will review some of the basic concepts of neuronal signaling that are important to the understanding of clinical neurophysiology.

Key Words

Action potential dipole ion channel membrane potential neurotransmission paroxysmal depolarization shift postsynaptic potential 


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Copyright information

© Humana Press Inc. 2007

Authors and Affiliations

  • Gregory L. Holmes
    • 1
  • Roustem Khazipov
    • 2
  1. 1.Section of Neurology, Neuroscience Center at DartmouthDartmouth Medical SchoolLebanon
  2. 2.Institut de Neurobiologie de la MéditerranéeMarseillesFrance

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