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In Vitro Fertilization for the Polycystic Ovary Syndrome

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Book cover Androgen Excess Disorders in Women

Part of the book series: Contemporary Endocrinology ((COE))

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Abstract

In vitro fertilization (IVF) is the final option for fertility treatment of all etiologies and must often be performed on women with polycystic ovaries or polycystic ovary syndrome (PCOS). Many women undergoing IVF are noted to have polycystic ovaries or PCOS. These women have ovaries that are more sensitive to ovarian stimulation, they develop more follicles, produce more oocytes, and are more prone to ovarian hyperstimulation syndrome (OHSS). This may be because of the increased vascularity of the ovaries as exemplified by increased ovarian stromal peak systolic blood flow velocity (Vmax) and increased levels of serum and intrafollicular vascular endothelial growth factor. In order to minimize the risk of OHSS, it is therefore necessary to commence ovarian stimulation with a smaller dose of gonadotropins. An alternative strategy could be to perform in vitro maturation of oocytes.

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© 2006 Humana Press Inc., Totowa, NJ

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Ba-Akdah, H., Demirtas, E., Holzer, H., Buckett, W., Tan, S.L. (2006). In Vitro Fertilization for the Polycystic Ovary Syndrome. In: Azziz, R., Nestler, J.E., Dewailly, D. (eds) Androgen Excess Disorders in Women. Contemporary Endocrinology. Humana Press. https://doi.org/10.1007/978-1-59745-179-6_36

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  • DOI: https://doi.org/10.1007/978-1-59745-179-6_36

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-663-4

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