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Endoscopic Therapy for Early Esophageal Cancer and Premalignant Lesions in Barrett’s Esophagus

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Endoscopic Oncology

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Abstract

The major medical consequence of Barrett’s esophagus (BE) is the potential risk of development of esophageal adenocarcinoma. It is the management of this cancer risk and early cancers that is the focus of endoscopic therapies. As the risk of cancer increases, the types of endoscopic therapies that can be applied become more invasive. These therapies involve removal of the esophageal mucosa and portions of the submucosa, thermal therapies to cauterize the neoplastic tissue, and the use of photochemical therapies that cause localized tissue necrosis. Case series suggest that these treatments are effective and in selected patients can be used in lieu of surgery or in patients who are not surgical candidates. However, randomized controlled trials are lacking.

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Author information

Authors and Affiliations

  1. Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL

    Ganapathy A. Prasad MD & Kenneth K. Wang MD

Authors
  1. Ganapathy A. Prasad MD
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  2. Kenneth K. Wang MD
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Editor information

Editors and Affiliations

  1. Oregon Health and Science University, Portland, OR

    Douglas O. Faigel MD, FACG, FASGE (Associate Professor of Medicine, Director of Endoscopy) (Associate Professor of Medicine, Director of Endoscopy)

  2. Hospital of the University of Pennsylvania, Philadelphia, PA

    Michael L. Kochman MD, FACP, FASGE (Professor of Medicine and Surgery, Co-Director Gastrointestinal Oncology) (Professor of Medicine and Surgery, Co-Director Gastrointestinal Oncology)

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© 2006 Humana Press, Totowa, NJ

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Prasad, G.A., Wang, K.K. (2006). Endoscopic Therapy for Early Esophageal Cancer and Premalignant Lesions in Barrett’s Esophagus. In: Faigel, D.O., Kochman, M.L. (eds) Endoscopic Oncology. Humana Press. https://doi.org/10.1007/978-1-59745-172-7_5

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  • DOI: https://doi.org/10.1007/978-1-59745-172-7_5

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-532-3

  • Online ISBN: 978-1-59745-172-7

  • eBook Packages: MedicineMedicine (R0)

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