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Mycobacterial Genomes

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Bacterial Genomes and Infectious Diseases

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Abstract

Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains a major cause of death around the world. Diseases caused by nontuberculous mycobacteria are increasingly associated with immunocompromised individuals. The availability of whole-genome sequences of mycobacterial species in the past several years has revolutionized TB research. This chapter provides an overview of the biology of mycobacteria and the diseases that they cause, with emphasis on how recent advances in genomics have improved our knowledge of the lifestyle and phylogeny of these organisms.

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Authors and Affiliations

  1. Montreal General Hospital Research Institute, McGill University Health Center, Montreal, Quebec, Canada

    David C. Alexander

  2. Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Ontario, Canada

    Jun Liu

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  1. David C. Alexander
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  2. Jun Liu
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Editors and Affiliations

  1. Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Ontario, Canada

    Voon L. Chan PhD

  2. Department of Paediatrics Department of Laboratory Medicine and Pathobiology Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada

    Philip M. Sherman MD, FRCPC

  3. Children’s Research Center, Our Lady’s Hospital for Sick Children, School of Medicine and Medical Science, Dublin, Ireland

    Billy Bourke MD, FRCPI

  4. Conway Institute for Biomolecular and Biomedical Research, University College, Dublin, Ireland

    Billy Bourke MD, FRCPI

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Alexander, D.C., Liu, J. (2006). Mycobacterial Genomes. In: Chan, V.L., Sherman, P.M., Bourke, B. (eds) Bacterial Genomes and Infectious Diseases. Humana Press. https://doi.org/10.1007/978-1-59745-152-9_9

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  • DOI: https://doi.org/10.1007/978-1-59745-152-9_9

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