Summary
Lichen Sclerosus is a chronic inflammatory disorder of the skin. Incidence in the western world is 1:300. In men, LS peaks between the 30 to 50 years. Both genders can be affected, although genital involvement is much more common in women. Possible etiologies for LS are the Koebner phenomenon, genetic susceptibility and autoimmunity, oxidative stress, and infection. Clinical presentation is usually white patches that seem to coalesce into “plaques” that can affect the prepuce and glans. It is not clear whether LS spreads by direct extension into the fossa navicularis and a portion of the anterior urethra, or if urethral involvement is secondary to LS induced meatal stenosis and subsequent “Littritis”. The classic radiographic appearance of LS anterior urethral stricture is a saw-toothed pattern. Surgical management of LS is primarily by staged urethroplasty.
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Virasoro, R., Jordan, G.H. (2008). Lichen Sclerosus. In: Brandes, S.B. (eds) Urethral Reconstructive Surgery. Current Clinical Urology. Humana Press. https://doi.org/10.1007/978-1-59745-103-1_3
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DOI: https://doi.org/10.1007/978-1-59745-103-1_3
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