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Preventive Cardiology pp 239–264Cite as

Subclinical Atherosclerosis

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Part of the book series: Contemporary Cardiology ((CONCARD))

Abstract

Risk stratification is a key component to recently developed consensus statements and guidelines for the prevention of cardiovascular disease (CVD), including the National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III and American College of Cardiology/American Heart Association (AHA) guidelines. In an effort to provide clinicians with guidance regarding the primary prevention of CVD and the identification of high-risk individuals, various organizations have developed consensus statements and clinical guidelines. Each stresses the centrality of risk stratification in tailoring individualized therapy and identifies high-risk individuals through categorical risk factor counting (categorical method) or continuous risk thresholds (continuous variables method). The NCEP ATP III, for example, varies the cholesterol thresholds for initiation of treatment and goals of therapy based on the presence of vascular disease or coexistent risk factors. Other consensus groups, including the Joint European Societies Expert Panel, recommend that pharmacological therapy be based on assessment of absolute risk.

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References

  1. Hag IU, Ramsay LE, Jackson PR, Wallis EJ. Prediction of coronary risk for primary prevention of coronary heart disease: a comparison of methods. QJ Med 1999; 92: 379–385.

    Google Scholar 

  2. Berenson GS, Srinivasan SR, Bao W, et al. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study. [see comment]. N Engl J Med 1998; 338(23): 1650–1656.

    Article  PubMed  CAS  Google Scholar 

  3. McGill HC Jr, McMahan CA. Determinants of atherosclerosis in the young. Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group. Am J Cardiol 1998; 82(10B): 26.

    Google Scholar 

  4. Faxon DP, Fuster V, Libby P, et al. Atherosclerotic Vascular Disease Conference: Writing Group III: pathophysiology. Circulation 2004; 109(21): 2617–2625.

    Article  PubMed  Google Scholar 

  5. Stary HC, Chandler AB, Dinsmore RE, et al. A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Arterioscler Thromb 1995; 92(15): 512–531.

    Google Scholar 

  6. Gore I, Tejada C. The quantitative appraisal of atherosclerosis. Am J Pathol 1957; 33: 875–885.

    PubMed  CAS  Google Scholar 

  7. Schoen FJ. Blood vessel. In: Abbas AK, ed. Robbins and Cotran Pathologic Basis of Disease. 7th ed. Elsevier, St. Louis, 2005, pp. 516–517.

    Google Scholar 

  8. Gould KL, Lipscomb K. Effects of coronary stenoses on coronary flow reserve and resistance. Am J Cardiol 1974; 34(1): 48–55.

    Article  PubMed  CAS  Google Scholar 

  9. Strong JP, Malcom GT, McMahan CA, et al. Prevalence and extent of atherosclerosis in adolescents and young adults: implications for prevention from the Pathobiological Determinants of Atherosclerosis in Youth Study. JAMA 1999; 281(8): 727–735.

    Article  PubMed  CAS  Google Scholar 

  10. Jaffer FA, O’Donnell CJ, Larson MG, et al. Age and sex distribution of subclinical aortic atherosclerosis: a magnetic resonance imaging examination of the Framingham Heart Study. Arterioscler Thromb 2002; 22(5): 849–854.

    Article  CAS  Google Scholar 

  11. Roberts WC. Preventing and arresting coronary atherosclerosis. Am Heart J 1995; 130(3 Pt 1): 580–600.

    Article  PubMed  CAS  Google Scholar 

  12. Newman WP 3rd, Freedman DS, Voors AW, et al. Relation of serum lipoprotein levels and systolic blood pressure to early atherosclerosis. The Bogalusa Heart Study. N Engl J Med 1986; 314(3): 138–144.

    Article  PubMed  Google Scholar 

  13. Goldstein JL, Kita T, Brown MS. Defective lipoprotein receptors and atherosclerosis. Lessons from an animal counterpart of familial hypercholesterolemia. N Engl J Med 1983; 309(5): 288–296.

    Article  PubMed  CAS  Google Scholar 

  14. Babiak J, Rudel LL. Lipoproteins and atherosclerosis. Baillieres Clinical Endocrinology&Metabolism 1987; 1(3): 515–550.

    Article  CAS  Google Scholar 

  15. Celermajer DS, Sorensen KE, Georgakopoulos D, et al. Cigarette smoking is associated with doserelated and potentially reversible impairment of endothelium-dependent dilation in healthy young adults. Circulation 1993; 88(5 Pt 1): 2149–2155.

    PubMed  CAS  Google Scholar 

  16. Zhu BQ, Sun YP, Sievers RE, et al. Passive smoking increases experimental atherosclerosis in cholesterol-fed rabbits.[see comment]. J Am Coll Cardiol 1993; 21(1): 225–232.

    PubMed  CAS  Google Scholar 

  17. Howard G, Wagenknecht LE, Burke GL, et al. Cigarette smoking and progression of atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) Study. [see comment]. JAMA 1998; 279(2): 119–124.

    Article  PubMed  CAS  Google Scholar 

  18. Schoenhagen P, Nissen SE. Coronary atherosclerosis in diabetic subjects: clinical significance, anatomic characteristics, and identification with in vivo imaging. Cardiol Clin 2004; 22(4): 527–540.

    Article  PubMed  Google Scholar 

  19. Mautner SL, Lin F, Roberts WC. Composition of atherosclerotic plaques in the epicardial coronary arteries in juvenile (type I) diabetes mellitus. Am J Cardiol 1992; 70(15): 1264–1268.

    Article  PubMed  CAS  Google Scholar 

  20. Crall FV Jr, Roberts WC. The extramural and intramural coronary arteries in juvenile diabetes mellitus: analysis of nine necropsy patients aged 19 to 38 years with onset of diabetes before age 15 years. Am J Med 1978; 64(2): 221–230.

    Article  PubMed  Google Scholar 

  21. Waller BF, Palumbo PJ, Lie JT, et al. Status of the coronary arteries at necropsy in diabetes mellitus with onset after age 30 years. Analysis of 229 diabetic patients with and without clinical evidence of coronary heart disease and comparison to 183 control subjects. Am J Med 1980; 69(4): 498–506.

    Article  PubMed  CAS  Google Scholar 

  22. Jorgensen L, Jenssen T, Joakimsen O, et al. Glycated hemoglobin level is strongly related to the prevalence of carotid artery plaques with high echogenicity in nondiabetic individuals: the Tromso study. Circulation 2004; 110(4): 466–470.

    Article  PubMed  CAS  Google Scholar 

  23. Rajala U, Laakso M, Paivansalo M, et al. Blood pressure and atherosclerotic plaques in carotid, aortic and femoral arteries in elderly Finns with diabetes mellitus or impaired glucose tolerance. J Hum Hypertens 2005; 19(1): 85–91.

    Article  PubMed  CAS  Google Scholar 

  24. McGill HC Jr, McMahan CA, Malcom GT, et al. Relation of glycohemoglobin and adiposity to atherosclerosis in youth. Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group. Arterioscler Thromb 1995; 15(4): 431–440.

    Google Scholar 

  25. Ellison RC, Zhang Y, Wagenknecht LE, et al. Relation of the metabolic syndrome to calcified atherosclerotic plaque in the coronary arteries and aorta. Am J Cardiol 2005; 95(10): 1180–1186.

    Article  PubMed  Google Scholar 

  26. Smith SC Jr, Milani RV, Arnett DK, et al. Atherosclerotic Vascular Disease Conference: Writing Group II: risk factors. Circulation 2004; 109(21): 2613–2616.

    Article  PubMed  Google Scholar 

  27. Duggirala R, Gonzalez Villalpando C, O’Leary DH, et al. Genetic basis of variation in carotid artery wall thickness. Stroke 1996; 27(5): 833–837.

    PubMed  CAS  Google Scholar 

  28. O’Donnell CJ, Chazaro I, Wilson PW, et al. Evidence for heritability of abdominal aortic calcific deposits in the Framingham Heart Study. Circulation 2002; 106(3): 337–341.

    Article  PubMed  Google Scholar 

  29. Nasir K, Michos ED, Rumberger JA, et al. Coronary artery calcification and family history of premature coronary heart disease: sibling history is more strongly associated than parental history. [see comment]. Circulation 2004; 110(15): 2150–2156.

    Article  PubMed  Google Scholar 

  30. Dubey RK, Imthurn B, Zacharia LC, et al. Hormone replacement therapy and cardiovascular disease: what went wrong and where do we go from here? Hypertension 2004; 44(6): 789–795.

    Article  PubMed  CAS  Google Scholar 

  31. Grady D, Herrington D, Bittner V, et al. Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II). [see comment] [erratum appears in JAMA 2002;288(9):1064]. JAMA 2002; 288(1): 49–57.

    Article  PubMed  Google Scholar 

  32. Rossouw JE, Anderson GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women’s Health Initiative randomized controlled trial. [see comment]. JAMA 2002; 288(3): 321–333.

    Article  PubMed  CAS  Google Scholar 

  33. Vaitkevicius PV, Fleg JL, Engel JH, et al. Effects of age and aerobic capacity on arterial stiffness in healthy adults. Circulation 1456; 88(4 Pt 1): 1456–1462.

    Google Scholar 

  34. Haas DC, Davidson KW, Schwartz DJ, et al. Depressive symptoms are independently predictive of carotid atherosclerosis. Am J Cardiol 2005; 95(4): 547–550.

    Article  PubMed  Google Scholar 

  35. Yusuf S, Hawken S, Ounpuu S, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. [see comment]. Lancet 2004; 364(99438): 937–952.

    Article  PubMed  Google Scholar 

  36. Greenland P, Abrams J, Aurigemma GP, et al. Prevention Conference V: beyond secondary prevention: identifying the high-risk patient for primary prevention: noninvasive tests of atherosclerotic burden: Writing Group III. Circulation 2000; 101(1): 4.

    Google Scholar 

  37. Sheridan S, Pignone M. Framingham-based tools to calculate the global risk of coronary heart disease. J Gen Intern Med 2003; 18(12): 1039–1052.

    Article  PubMed  Google Scholar 

  38. Liao Y, McGee DL, Cooper RS. Prediction of coronary heart disease mortality in blacks and whites: pooled data from two national cohorts. Am J Cardiol 1999; 84(1): 31–36.

    Article  PubMed  CAS  Google Scholar 

  39. Liao Y, McGee DL, Cooper RS, et al. How generalizable are coronary risk prediction models? Comparison of Framingham and two national cohorts. Am Heart J 1999;137(5):837–845.

    Article  PubMed  CAS  Google Scholar 

  40. Grundy SM, D’Agostino RB Sr, Mosca L, et al. Cardiovascular risk assessment based on US cohort studies: findings from a National Heart, Lung, and Blood institute workshop. Circulation 2001; 104(4): 491–496.

    PubMed  CAS  Google Scholar 

  41. D’Agostino RB Sr, Grundy S, Sullivan LM, et al. Validation of the Framingham coronary heart disease prediction scores: results of a multiple ethnic groups investigation. [see comment]. JAMA 2001; 286(2): 180–187.

    Article  PubMed  Google Scholar 

  42. McMahan CA, Gidding SS, Fayad ZA, et al. Risk scores predict atherosclerotic lesions in young people. Arch Intern Med 2005; 165(8): 883–890.

    Article  PubMed  Google Scholar 

  43. Cohn PF, Fox KM. Silent myocardial ischemia. Circulation 2003; 108: 1263–1277.

    Article  PubMed  Google Scholar 

  44. Wackers FJ, Young LH, Inzucchi SE, et al. Detection of silent myocardial ischemia in asymptomatic diabetic subjects: the DIAD study. [see comment] [erratum appears in Diabetes Care 2005;28(2):504]. Diabetes Care 2004; 27(8): 1954–1961.

    Article  PubMed  Google Scholar 

  45. Resnick HE, Foster GL. Prevalence of elevated ankle-brachial index in the United States 1999 to 2002. Am J Med 2005; 118(6): 676–679.

    Article  PubMed  Google Scholar 

  46. Hiatt WR. Medical treatment of peripheral arterial disease and claudication. N Engl J Med 2001; 344(21): 1608–1621.

    Article  PubMed  CAS  Google Scholar 

  47. Choi CJ, KramerCM. MR imaging of atherosclerotic plaque. Radiol Clin North Am 2002; 40(4): 887–898.

    Article  PubMed  Google Scholar 

  48. Anand DJ, Lahiri A. EBCT coronary calcium imaging for the early detection of coronary artery disease in asymptomatic individuals. Br J Cardiol 2003; 10(4): 273–280.

    Google Scholar 

  49. Agatston AS, Janowitz WR, Hildner FJ, et al. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol 1990; 15(4): 827–832.

    Article  PubMed  CAS  Google Scholar 

  50. Callister TQ, Cooil B, Raya SP, et al. Coronary artery disease: improved reproducibility of calcium scoring with an electron-beam CT volumetric method. [see comment]. Radiology 1998; 208(3): 807–814.

    PubMed  CAS  Google Scholar 

  51. Salazar HP, Raggi P. Usefulness of electron-beam computed tomography. Am J Cardiol 2002; 89(4A): 21.

    Google Scholar 

  52. Bild DE, Bluemke DA, Burke GL, et al. Multi-ethnic study of atherosclerosis: objectives and design. Am J Epidemiol 2002; 156(9): 871–881.

    Article  PubMed  Google Scholar 

  53. Davignon J, Ganz P. Role of endothelial dysfunction in atherosclerosis. Circulation 2004; 109(23 Suppl 1): 15.

    Google Scholar 

  54. Anderson TJ. Assessment and treatment of endothelial dysfunction in humans. J Am Coll Cardiol 1999; 34(3): 631–638.

    Article  PubMed  CAS  Google Scholar 

  55. Bonetti PO, Pumper GM, Higano ST, et al. Noninvasive identification of patients with early coronary atherosclerosis by assessment of digital reactive hyperemia. J Am Coll Cardiol 2004; 44(11): 2137–2141.

    Article  PubMed  Google Scholar 

  56. Celermajer DS, Sorensen KE, Gooch VM. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 1992; 340: 1111–1115.

    Article  PubMed  CAS  Google Scholar 

  57. Tracy RP. Inflammation in cardiovascular disease: cart, horse, or both? [see comment]. Circulation 2000; 97(20): 2000–2002.

    Google Scholar 

  58. Loscalzo J, Bonow RO, Jacobs AK. Coronary calcium screening and the American Heart Association news embargo. Circulation 2004; 110(23): 3504–3505.

    Article  PubMed  Google Scholar 

  59. Pearson TA, Mensah GA, Alexander RW, et al. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. [see comment]. Circulation 2003; 107(3): 499–511.

    Article  PubMed  Google Scholar 

  60. Malinow MR, Bostom AG, Krauss RM. Homocyst(e)ine, diet, and cardiovascular diseases: a statement for healthcare professionals from the Nutrition Committee, American Heart Association. [see comment]. Circulation 1999; 99(1): 178–182.

    PubMed  CAS  Google Scholar 

  61. Niebauer J, Hambrecht R, Velich T, et al. Attenuated progression of coronary artery disease after 6 years of multifactorial risk intervention: role of physical exercise. Circulation 1997; 96(8): 2534–2541.

    PubMed  CAS  Google Scholar 

  62. Watts GF, Lewis B, Brunt JN, et al. Effects on coronary artery disease of lipid-lowering diet, or diet plus cholestyramine, in the St Thomas’ Atherosclerosis Regression Study (STARS) [see comment]. Lancet1992; 339(8793): 563–569.

    Article  PubMed  CAS  Google Scholar 

  63. Blankenhorn DH, Johnson RL, Mack WJ, et al. The influence of diet on the appearance of new lesions in human coronary arteries. [see comment]. JAMA 1990; 263(12): 1646–1652.

    Article  PubMed  CAS  Google Scholar 

  64. Rothenbacher D, Hoffmeister A, Brenner H, et al. Physical activity, coronary heart disease, and inflammatory response. Arch Intern Med 2003; 163(10): 1200–1205.

    Article  PubMed  Google Scholar 

  65. Desai MY, Nasir K, Rumberger JA, et al. Relation of degree of physical activity to coronary artery calcium score in asymptomatic individuals with multiple metabolic risk factors. Am J Cardiol 2004; 94(6): 729–732.

    Article  PubMed  CAS  Google Scholar 

  66. Pate RR, Pratt M, Blair SN, et al. Physical activity and public health. A recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine. [see comment]. JAMA 1995; 273(5): 402–407.

    Article  PubMed  CAS  Google Scholar 

  67. Balk EM, Karas RH, Jordan HS, et al. Effects of statins on vascular structure and function: a systematic review. Am J Med 2004; 117(10): 775–790.

    Article  PubMed  CAS  Google Scholar 

  68. Taylor AJ, Sullenberger LE, Lee HJ, et al. Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins. [see comment]. Circulation 2004; 110(23): 3512–3517.

    Article  PubMed  CAS  Google Scholar 

  69. Ericsson CG, Hamsten A, Nilsson J, et al. Angiographic assessment of effects of bezafibrate on progression of coronary artery disease in young male postinfarction patients. Lancet 1996; 347(9005): 849–853.

    Article  PubMed  CAS  Google Scholar 

  70. Manninen V, Elo MO, Frick MH, et al. Lipid alterations and decline in the incidence of coronary heart disease in the Helsinki Heart Study. JAMA 1988; 260(5): 641–651.

    Article  PubMed  CAS  Google Scholar 

  71. Grundy SM, Cleeman JI, Merz CN, et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. [erratum appears in Circulation 2004;110(6):763]. Circulation 2004; 110(2): 227–239.

    Article  PubMed  Google Scholar 

  72. Nathan DM, Lachin J, Cleary P, et al. Intensive diabetes therapy and carotid intima-media thickness in type 1 diabetes mellitus. [see comment]. N Engl J Med 2003;348 (23): 2294–2303.

    Google Scholar 

  73. Gaede P, Vedel P, Larsen N, et al. Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. [see comment]. N Engl J Med 2003; 348(5): 383–393.

    Article  PubMed  Google Scholar 

  74. Hetzel J, Balletshofer B, Rittig K, et al. Rapid effects of rosiglitazone treatment on endothelial function and inflammatory biomarkers (early online release). Arterioscler Thromb Vasc Biol 2005; 25(9): 1804–1809.

    Article  PubMed  CAS  Google Scholar 

  75. Neal B, MacMahon S, Chapman N, et al. Effects of ACE inhibitors, calcium antagonists, and other bloodpressure-lowering drugs: results of prospectively designed overviews of randomised trials. Blood Pressure Lowering Treatment Trialists’ Collaboration. [see comment]. Lancet 2000; 356(9246): 1955–1964.

    Article  PubMed  CAS  Google Scholar 

  76. Da Cunha V, Tham DM, Martin-McNulty B, et al. Enalapril attenuates angiotensin II-induced atherosclerosis and vascular inflammation. Atherosclerosis 2005; 178(1): 9–17.

    Article  PubMed  CAS  Google Scholar 

  77. Yusuf S, Sleight P, Pogue J, et al. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. [see comment] [erratum appears in 2000;342(18):1376]. N Engl J Med 2000; 342(3): 145–153.

    Article  PubMed  CAS  Google Scholar 

  78. Ellison RC. AHA Science Advisory on wine and health: a confusing message about alcohol consumption. [comment]. Circulation 2001; 104(13): 25.

    Google Scholar 

  79. Goldberg IJ, Mosca L, Piano MR, et al. AHA Science Advisory: wine and your heart: a science advisory for healthcare professionals from the Nutrition Committee, Council on Epidemiology and Prevention, and Council on Cardiovascular Nursing of the American Heart Association. [see comment]. Circulation 2001; 103(3): 472–475.

    PubMed  CAS  Google Scholar 

  80. Erkkila AT, Lichtenstein AH, Mozaffarian D, et al. Fish intake is associated with a reduced progression of coronary artery atherosclerosis in postmenopausal women with coronary artery disease. [see comment]. Am J Clin Nutr 2004; 80(3): 626–632.

    PubMed  Google Scholar 

  81. Krauss RM, Eckel RH, Howard B, et al. AHA Dietary Guidelines: revision 2000: a statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Circulation 2000; 102(18): 2284–2299.

    PubMed  CAS  Google Scholar 

  82. Rimm EB, Stampfer MJ. Antioxidants for vascular disease. Med Clin North Am 2000; 84(1): 239–249.

    Article  PubMed  CAS  Google Scholar 

  83. Kouraklis G, Patapis P, Misiakos E, et al. Effects of acetylsalicylic acid on experimental atherogenesis induced in rabbits. Int Angiol 2004; 23(2): 139–143.

    PubMed  CAS  Google Scholar 

  84. Anonymous. Final report on the aspirin component of the ongoing Physicians’ Health Study. Steering Committee of the Physicians’ Health Study Research Group. [see comment]. N Engl J Med 1989; 321(3): 129–135.

    Article  Google Scholar 

  85. Peto R, Gray R, Collins R, et al. Randomised trial of prophylactic daily aspirin in British male doctors. Br Med J (Clin Res Ed) 1988; 296(6618): 313–316.

    Article  CAS  Google Scholar 

  86. Ridker PM, Cook NR, Lee IM, et al. A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women. [see comment]. N Engl J Med 2005; 352(13): 1293–1304.

    Article  PubMed  CAS  Google Scholar 

  87. Pearson TA, Blair SN, Daniels SR, et al. AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke: 2002 Update: Consensus panel guide to comprehensive risk reduction for adult patients without coronary or other atherosclerotic vascular diseases. American Heart Association Science Advisory and Coordinating Committee. Circulation 2002; 106(3): 388–391.

    Article  PubMed  Google Scholar 

  88. Colwell JA, American Diabetes Association. Aspirin therapy in diabetes. Diabetes Care 2004; 27(Suppl 1): S72–73.

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT

    Rahman Shah MD

  2. Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT

    JoAnne Micale Foody MD

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  1. Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT

    Joanne Micale Foody MD

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Shah, R., Foody, J.M. (2006). Subclinical Atherosclerosis. In: Foody, J.M. (eds) Preventive Cardiology. Contemporary Cardiology. Humana Press. https://doi.org/10.1007/978-1-59745-096-6_13

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  • DOI: https://doi.org/10.1007/978-1-59745-096-6_13

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