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Gene-Expression Profiling and Restenosis

  • Chapter
Essentials of Restenosis

Part of the book series: Contemporary Cardiology ((CONCARD))

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Abstract

A central goal of molecular cardiology is the characterization of molecular mechanisms regulating complex cardiovascular functions and the identification of diseaseassociated gene-expression patterns. Gene transcription is the most important regulatory mechanism by which a phenotype and functional state of a cell and a tissue is determined. Therefore, qualitative and quantitative assessment is the first step into the nature of biological processes. When small cell numbers are used, messenger RNA (mRNA) abundance is easier to investigate in a comprehensive manner than protein expression.

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Author information

Authors and Affiliations

  1. Deutsches Herzzentrum München, München, Germany

    Dietlind Zohlnhöfer MD

  2. Herz Zentrum Bad Krozingen, Bad Krozingen, Germany

    Franz-Josef Neumann MD

Authors
  1. Dietlind Zohlnhöfer MD
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  2. Franz-Josef Neumann MD
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Editor information

Editors and Affiliations

  1. Thoraxcenter, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands

    Henricus J. Duckers MD, PhD  & Patrick W. Serruys MD, PhD  & 

  2. The Nabel Lab, Genome Technology Branch, NHGRI Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD

    Elizabeth G. Nabel MD

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© 2007 Humana Press Inc.

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Zohlnhöfer, D., Neumann, FJ. (2007). Gene-Expression Profiling and Restenosis. In: Duckers, H.J., Nabel, E.G., Serruys, P.W. (eds) Essentials of Restenosis. Contemporary Cardiology. Humana Press. https://doi.org/10.1007/978-1-59745-001-0_9

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  • DOI: https://doi.org/10.1007/978-1-59745-001-0_9

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-491-3

  • Online ISBN: 978-1-59745-001-0

  • eBook Packages: MedicineMedicine (R0)

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