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Clinical Presentation of Restenosis

  • Chapter
Essentials of Restenosis

Part of the book series: Contemporary Cardiology ((CONCARD))

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Abstract

Coronary artery disease remains a major cause of mortality and morbidity. Unstable angina and non-Q-wave myocardial infarction (MI) account for approx 2–2.5 million hospitalizations worldwide (1). Furthermore, unstable angina is associated with a high risk of MI or death if treated inadequately (2). Advances in clinical therapeutics and the introduction of percutaneous coronary therapy by Grüntzig and coworkers in the late 1970s have revolutionalized the way ischemic heart disease is managed in clinical practice (3). Percutaneous coronary intervention (PCI) is now the primary mode of treatment for managing occlusive coronary disease in symptomatic patients. However, the practice of using stand-alone balloon angioplasty has largely been superseded by the addition of stent deployment to improve procedural success and outcome ((4)–(7)). The advent of the stent era and improvements in stent technology has enabled treatment of more complex and difficult coronary lesions, with multivessel stenting and techniques such as direct stenting (8), increasing in frequency.

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  1. Cardiovascular Centre Aalst, OLV Hospital, Aalst, Belgium

    Ganesh Manoharan MBBCh, MD, MRCPI, Giedrius Davidavicius MD & William Wijns MD, PhD

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  2. Giedrius Davidavicius MD
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  1. Thoraxcenter, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands

    Henricus J. Duckers MD, PhD  & Patrick W. Serruys MD, PhD  & 

  2. The Nabel Lab, Genome Technology Branch, NHGRI Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD

    Elizabeth G. Nabel MD

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© 2007 Humana Press Inc.

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Manoharan, G., Davidavicius, G., Wijns, W. (2007). Clinical Presentation of Restenosis. In: Duckers, H.J., Nabel, E.G., Serruys, P.W. (eds) Essentials of Restenosis. Contemporary Cardiology. Humana Press. https://doi.org/10.1007/978-1-59745-001-0_3

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  • DOI: https://doi.org/10.1007/978-1-59745-001-0_3

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