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Arterial Remodeling

  • Chapter
Essentials of Restenosis

Part of the book series: Contemporary Cardiology ((CONCARD))

Abstract

Arterial remodeling is recognized as an important determinant in most vascular pathology in which narrowing of the lumen is the predominant feature. Not only expansive remodeling, for example, enlargement, but also constrictive remodeling, for example, shrinkage, is observed in arterial occlusive disease (1–5). Expansive remodeling prevents and constrictive remodeling accelerates narrowing of the lumen (1–5). Also in restenosis after balloon angioplasty, in both experimental research (6–8) as well as in humans (9), constrictive remodeling is the most important determinant of luminal renarrowing (10).

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Authors and Affiliations

  1. Laboratory of Experimental Cardiology, Heart Lung Institute, University Medical Center Utrecht, Utrecht, The Netherlands

    Gerard Pasterkamp PhD & Dominique de Kleijn PhD

  2. Department of Cardiology, St. Michael’s Hospital, Toronto, Ontario, Canada

    Bradley H. Strauss MD, PhD

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  1. Gerard Pasterkamp PhD
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  2. Bradley H. Strauss MD, PhD
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  3. Dominique de Kleijn PhD
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Editors and Affiliations

  1. Thoraxcenter, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands

    Henricus J. Duckers MD, PhD  & Patrick W. Serruys MD, PhD  & 

  2. The Nabel Lab, Genome Technology Branch, NHGRI Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD

    Elizabeth G. Nabel MD

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Pasterkamp, G., Strauss, B.H., de Kleijn, D. (2007). Arterial Remodeling. In: Duckers, H.J., Nabel, E.G., Serruys, P.W. (eds) Essentials of Restenosis. Contemporary Cardiology. Humana Press. https://doi.org/10.1007/978-1-59745-001-0_13

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