Abstract
Erectile dysfunction (ED) is defined as the consistent or recurrent inability to attain and/or maintain a penile erection sufficient for sexual performance and is a common sexual dysfunction especially among men with diabetes (1). Sexual dysfunctions can include problems with libido, erectile function, and ejaculation. Although previously the term impotence was used interchangeably for all aspects of sexual dysfunction, this vague term led to confusion. Thus, in 1992, a National Institutes of Health consensus conference recommended that the term erectile dysfunction be used to describe problems relating to penile erections (2).
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References
Meuleman E, Broderick G, Meng Tan H. Clinical evaluation and the doctor-patient dialogue. In: Jardin A, Wagner G, Khoury S, Giuliano F, Padma-Nathan H, Rosen R, eds. Erectile Dysfunction. Plymbridge Distributors, Plymouth, UK, 2000, pp. 115–138.
NIH Consensus Development Panel on Impotence. Impotence. JAMA 1993;270:83–90.
Kinsey AC, Pomeroy WB, Martin CE. Sexual Behavior in the Human Male. WB Saunders, Philadelphia, 1998, pp. 235–238.
Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol 1994;151:54–61.
Morillo LE, Diaz J, Estevez E, et al. Prevalence of erectile dysfunction in Columbia, Ecuador, and Venezuela: a population-based study (DENSA). Int J Impot Res 2002;14(Suppl. 2):S10–S18.
GD Braunstein. Impotence in diabetic men. Mt Sinai J Med 1987;54:236–240.
Romeo JH, Seftel AD, Madhun ZT, Aron DC. Sexual function in men with diabetes type 2: association with glycemic control. J Urol 2000;163:788–791.
Derby CA, Araujo AB, Johannes CB, Feldman HA, McKinlay JB. Measurement of erectile dysfunction in population-based studies: the use of a single question self-assessment in the Massachusetts Male Aging Study. Int J Impot Res 2000;12:197–204.
Italiano G, Calabro A, Spini S, Ragazzi E, Pagano F. Functional response of cavernosal tissue to distension. Urol Res 1998;26:39–44.
Gondre M, Christ GJ. Endothelin-1-induced alterations in phenylephrine-induced contractile responses are largely additive in physiologically diverse rabbit vasculature. J Pharmacol Exp Ther 1998;286:635–642.
Masters WH, Johnson VE. Sex after sixty-five. Reflections 1977;12:31–43.
Blanco R, Saenz de Tejada I, Goldstein I, Krane RJ, Wotiz HH, Cohen RA. Dysfunctional penile cholinergic nerves in diabetic impotent men. J Urol 1990;144:278–280.
Saenz de Tejada I, Goldstein I, Azadzoi K, Krane RJ, Cohen RA. Impaired neurogenic and endothelium-mediated relaxation of penile smooth muscle from diabetic men with impotence. N Engl J Med 1989;320:1025–1030.
Breza J, Aboseif SR, Orvis BR, Lue TF, Tanagho EA. Detailed anatomy of penile neurovascular structures: surgical significance. J Urol 1989;141:437–443.
Davidson JM, Camargo CA, Smith ER. Effects of androgen on sexual behavior in hypogonadal men. J Clin Endocrinol Metab 1979;48:955–958.
Drugs that cause sexual dysfunction: An update. Med Lett 1992;34:73–74.
Lue TF. Erectile dysfunction. N Engl J Med 2000;342:1802–1813.
Wang CJ, Shen SY, Wu CC, Huang CH, Chiang CP. Penile blood flow study in diabetic impotence. Urol Int 1993;50:209–212.
Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A. The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology 1997;49:822–830.
Padma-Nathan H, Stecher VJ, Sweeney M, Orazem J, Tseng LJ, Deriesthal H. Minimal time to successful intercourse after sildenafil citrate: results of a randomized, double-blind, placebo-controlled trial. Urology 2003;62:400–403.
Sildenafil package insert. Pfizer. September 2002.
Hellstrom WJ. Vardenafil: a new approach to the treatment of erectile dysfunction. Curr Urol Rep 2003;4:479–487.
Levitra package insert. Bayer Pharmaceuticals. August 2003.
Cialis package insert. Lilly ICOS. November 2003.
Dula E, Bukofzer S, Perdok R, George M, for the apomorphine SL Study Group. Double-blind, crossover comparison of 3 mg apomorphine SL with placebo and with 4 mg apomorphine SL in male erectile function. Eur Urol 2001;39:558–564.
Mann K, Klingler T, Noe S, Roschke J, Muller S, Benkert O. Effects of yohimbine on sexual experiences and nocturnal penile tumescence and rigidity in erectile dysfunction. Arch Sex Behav 1996;25:1–16.
Brindley GS. Cavernosal alpha-blockade: a new technique for investigating and treating erectile impotence. Br J Psychiatry 1983;143:332–337.
Zorgniotti AW, Lefleur RS. Auto-injection of the corpus cavernosum with a vasoactive drug combination for vasculogenic impotence. J Urol 1985;133:39–41.
Krane, Goldstein I, Saenz de Tejada I. Impotence. N Engl J Med 1989;321:1648–1659.
Linet OI, Ogrinc FG. Efficacy and safety of intracavernosal alprostadil in men with erectile dysfunction. The Alprostadil Study Group. N Engl J Med 1996;334:873–877.
Weiss JN, Badlani GH, Ravalli R, Brettschneider N. Reasons for high drop-out rate with self-injection therapy for impotence. Int J Impot Res 1994;6:171–174.
Gupta R, Kirschen J, Barrow RC 2nd, Eid JF. Predictors of success and risk factors for attrition in the use of intracavernous injection. J Urol 1997;157:1681–1686.
Padma-Nathan Hellstrom WJ, Kaiser FE, Labasky RF, et al. Treatment of men with erectile dysfunction with transurethral alprostadil. Medicated Urethral System for Erection (MUSE) Study Group. N Engl J Med 1997;336:1–7.
Nadig PW, Ware JC, Blumoff R. Noninvasive device to produce and maintain an erection-like state. Urology 1986;27:126–131.
Lewis R. Surgery for Erectile Dysfunction. In: Walsh PC, Retik AB, Vaughan ED, Wein AJ, eds. Campbell’s Urology, 7th ed. WB Saunders, Philadelphia, 1998, pp. 1215–1226.
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© 2006 Humana Press Inc., Totowa, NJ
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Snow, K.J. (2006). Erectile Dysfunction. In: Mantzoros, C.S. (eds) Obesity and Diabetes. Contemporary Diabetes. Humana Press. https://doi.org/10.1007/978-1-59259-985-1_21
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DOI: https://doi.org/10.1007/978-1-59259-985-1_21
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