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Zinc and Eye Health

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Handbook of Nutrition and Ophthalmology

Part of the book series: Nutrition and Health ((NH))

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Abstract

Zinc plays an essential role in growth, neurodevelopment, immunity, reproduction, and a wide range of physiological processes, including metabolism of nucleic acids, protein, and lipids, synthesis of hormones, and apoptosis. Zinc deficiency is common in developing countries worldwide (1), and zinc supplementation studies suggest that zinc deficiency may be widespread in North America among infants, children, and pregnant women (2). Acrodermatitis enteropathica, an inborn error of zinc metabolism, is characterized by compromised immunity and skin and ocular findings. Zinc deficiency can also occur in Crohn disease and among individuals receiving total parenteral nutrition without sufficient zinc. The retina and choroid contain the highest concentrations of zinc of any tissue in the human body. Zinc plays an important role in eye health, and recent investigations have demonstrated a causal link between zinc status and age-related macular degeneration. The role of zinc in age-related maculopathy and age-related macular degeneration are presented in greater detail in Chapter 4, under Subheading 5.4.

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© 2007 Humana Press Inc., Totowa, NJ

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(2007). Zinc and Eye Health. In: Handbook of Nutrition and Ophthalmology. Nutrition and Health. Humana Press. https://doi.org/10.1007/978-1-59259-979-0_8

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  • DOI: https://doi.org/10.1007/978-1-59259-979-0_8

  • Publisher Name: Humana Press

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