Abstract
Metastases are the neoplasms most commonly seen by both orthopaedic and neurosurgeons, and the spine is the site most frequently involved (9,20). At autopsy, more than 70% of patients who die of cancer have vertebral metastases (23). Although nearly all malignancies may metastasize to bone, carcinoma of breast and bronchogenic origin, lymphoma, and multiple myeloma account for half of all spinal metastases (4,11,12,20,35,38,51).
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References
Abumi K, Panjabi MM, Kramer KM, Duranceau J, Oxland T, Crisco JJ. Biolmechanical evaluation of lumbar spinal stability after graded facetectomy. Spine 1990; 15:1142–1147.
Bauer HC. Posterior decompression and stabilization for spinal metastases: analysis of sixty-seven consecutive patients. J Bone Joint Surg 1997; 79:514–523.
Bilsky MH, Boland P, Lis E, Raizer JJ, Healey JH. Single stage posterolateral transpedicle approach for spondylectomy, epidural decompression, and circumferential fusion of spinal metastases. Spine 2000; 25:2240–2250.
Black P. Spinal metastasis: current status and recommended guidelines for management. Neurosurgery 1979; 5:726–746.
Bridwell KH, Jenny AB, Saul T, Rich KM, Grubb RL. Posterior segmental spinal instrumentation (PSSI) with posterolateral decompression and debulking for metastatic thoracic and lumbar spine disease: limitations of the technique. Spine 1988; 13:1383–1394.
Bruckman, JE, and Bloomer, WD. Management of spinal cord compression. Semin Oncol 1978; 5:135–140.
Constans JP, De Divitiis E, Donzelli R, Spaziante R, Meder JF, Haye C. Spinal metastasis with neurological manifestations: review of 600 cases. J Neurosurg 1983; 59:111–118.
Cybulski GR, Stone JL, Opesanmi O. Spinal cord decompression via a modified costotransversectomy approach combined with posterior instrumentation for management of metastatic neoplasms of the thoracic spine. Surg Neurol 1991; 35:280–285.
Dahlin DC. Bone Tumors: General Aspects and Data on 6221 Cases. 3rd ed. Springfield, IL: Charles C Thomas; 1978.
Denis F. The three column spine and its significance in the classification of acute thoracolumbar spine injuries. Spine 1983; 8:817–831.
Dewald RL, Bridwell KH, Prodromas C, Rodts MF. Reconstructive spinal surgery as palliation for metastatic malignancies of the spine. Spine 1985; 10:21–26.
Drury AB, Palmer PH, Highman WJ. Carcinomatous metastases to the vertebral bodies. J Clin Pathol 1964; 17:448–460.
Fidler MW. Anterior decompression and stabilisation of metastatic spinal fractures. J Bone Joint Surg 1986; 68:83–90.
Flynn JC, Price CT. Sexual complications of anterior fusion of the lumbar spine. Spine 1984; 9:489–492.
Gilbert RW, Kim JH, Posner JB. Epidural spinal cord compression from metastatic tumor: diagnosis and treatment. Annals Neurol 1978; 3:40–51.
Greenberg HS, Kim JH, Posner JB. Epidural spinal cord compression from metastatic tumor. Ann Neurol 1980; 8:361–366.
Hammerberg KW. Surgical treatment of metastatic spine disease. Spine 1992; 17:1148–1153.
Harrington KD. Current concept review. Metastatic disease of the spine. J Bone Joint Surg 1986; 68:1110–1115.
Harrington KD. Anterior decompression and stabilization of the spine as a treatment for vertebral collapse and spinal cord compression from metastatic malignancy. Clin Orthop 1988; 233:177–197.
Harrington KD. Metastatic diseases of the spine. In: Harrington, KD ed. Orthopaedic Management of Metastatic Bone Disease. St. Louis, MO: CV Mosby; 1988:309–383.
Hipp JA, Springfield DS, Hayes WC. Predicting pathologic fracture risk in the management of metastatic bone defects. Clin Orthop 1995; 312:120–135.
Hosono N, Yonenobu K, Fuji T, Ebara S, Yamashita K, Ono K. Orthopaedic management of spinal metastases. Clin Orthop 1995; 312:148–159.
Jaffe HL. Tumors and Tumorous Conditions of the Bone and Joints. Philadelphia, PA: Lea and Febiger; 1958.
Klekamp J, Samii H. Surgical results for spinal metastases. Acta Neurochir (Wein) 1998; 140:957–967.
Kostuik JP, Errico TJ, Gleason TF, Errico CC. Spinal stabilization of vertebral column tumors. Spine 1988; 13:250–256.
Manabe S, Tateishi A, Abe M, Ohno T. Surgical treatment of metastatic tumors of the spine. Spine 1989; 14:41–47.
McAfee PC, Bohlman HH, Ducker T, Eismont FJ. Failure of stabilization of the spine with methylmethacrylate: a retrospective review of twenty-four cases. J Bone Joint Surg 1986; 68:1145–1157.
Martin NS, Williamson J. The role of surgery in the treatment of malignant tumors of the spine. J Bone Joint Surg 1970; 52:227–237.
McLain RF. Endoscopically assisted decompression for metastatic thoracic neoplasms. Spine 1998; 23:1130–1135.
McLain RF. Spinal cord decompression: an endoscopically assisted approach for metastatic tumors. Spinal Cord 2001; 39:482–487.
McLain RF, Weinstein JN. Tumors of the spine. In: Herkowitz HN, Garfin SR, Balderston RA, et al. eds. Rothman-Simeone: The Spine. Philadelphia, PA: WB Saunders; 1999:1171–1206.
Millburn L, Hibbs GC, Hendrickson FR. Treatment of spinal cord compression from metastatic carcinoma. Cancer 1968; 21:447–452.
Muhlbauer M, Pfister W, Eyb R, et al. Noncontiguous spinal metastases and plasmacytomas should be operated on through a single posterior midline approach, and circumferential decompression should be performed with individual reconstruction. Acta Neurochiurgica (Wien) 2000; 142:1219–1230.
Murphy KJ, Deramond H. Percutaneous vertebroplasty in benign and malignant disease. Neur Imag Clin 2000; 10:535–545.
Nather A, Bose K. The results of decompression of cord or cauda equina compression from metastatic extradural tumors. Clin Orthop 1982; 169:103–108.
Nicholls PJ, Jarecky TW. The value of posterior decompression by laminectomy for malignant tumors of the spine. Clin Orthop 1985; 201:210–213.
Overby MC, Rothman AS. Anterolateral decompression for metastatic epidural spinal cord tumors: results of a modified costotransversectomy approach. J Neurosurg 1985; 62:344–348.
Perrin RG, McBroom RJ. Anterior vs. posterior decompression for symptomatic spinal metastasis. Can J Neurol Sci 1987; 14:75–80.
Shimizu, K, Shikata, J, Iida, H, Iwasaki R, Yoshikawa J, Yamamuro T. Posterior decompression and stabilization for multiple metastatic tumors of the spine. Spine 1992; 17:1400–1404.
Siegal T, Siegal T, Robin G, Lubetzki-Korn I, Fuks Z. Anterior decompression of the spine for metastatic epidural cord compression: A promising avenue of therapy? Ann Neurol 1982; 11:28–34.
Siegal T, Siegal T. Surgical decompression of anterior and posterior malignant epidural tumors compressing the spinal cord: a prospective study. Neurosurg 1985; 17:424–431.
Siegal T, Tiqva P, Siegal T. Vertebral body resection for epidural compression by malignant tumors: results of forty-seven consecutive operative procedures. J Bone Joint Surg 1985; 67:375–382.
Sundaresan N, Sachdev VP, Holland JF, et al. Surgical treatment of spinal cord compression from epidural metastasis. J Clin Oncol 1995; 13:2330–2335.
Tomita K, Kawahara, N, Kobayashi T, Yoshida A, Murakami H, Akamaru T. Surgical strategey for spinal metastases. Spine 2001; 26:298–306.
Tomita T, Galicich JH, and Sundaresan N. Radiation therapy for spinal epidural metastases with complete block. Acta Radiol Oncol 1983; 22:135–143.
Weigel B, Maghsudi M, Neumann C, Kretschmer R, Muller FJ, Nerlich M. Surgical management of symptomatic spinal metastases: postoperative outcome and quality of life. Spine 1999; 24:2240–2246.
Weinstein JN. Surgical approach to spine tumors. Orthopaedics 1989; 12:897–905.
Weinstein JN, McLain RF. Primary tumors of the spine. Spine 1987; 12:843–851.
West JL. Posterior instrumentation for reconstruction in spine tumors. Sem Spine Surg 2000; 12:38–41.
White AA, Panjabi MM. Surgical constructs employing methylmethacrylate. In: White AA, Panjabi MM, eds. Clinical Biomechanics of the Spine. Philadelphia, PA: JB Lippincott; 1978:423–431.
Young RF, Post EM, King GA. Treatment of spinal epidural metastases. J Neurosurg 1980; 53:741–748.
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Babat, L.B., McLain, R.F. (2006). Metastatic Disease of the Thoracolumbar Spine. In: McLain, R.F., Lewandrowski, KU., Markman, M., Bukowski, R.M., Macklis, R., Benzel, E.C. (eds) Cancer in the Spine. Current Clinical Oncology. Humana Press. https://doi.org/10.1007/978-1-59259-971-4_31
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