Abstract
The term mesothelioma has been applied to two very different neoplasms. The first is the diffuse malignant mesothelioma (DMM), which covers the serosal surface, has both epithelioid and mesenchymal characteristics histologically, is virtually always fatal, and is caused by asbestos. The second is the fibrous mesothelioma, which forms a discrete mass, usually can be cured by resection, and is not related to asbestos. It is derived from the submesothelial fibroblast and thus has a histogenesis different from DMM. Its radio- graphic appearance as a baseball in the chest differs dramatically from DMM, but a needle biopsy of the tumor may show hyperchromatic spindle cells difficult to differentiate from a fibrosarcomatous or desmoplastic subtype of DMM.
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(2005). Pleural Tumors. In: Lung Pathology. Current Clinical Pathology. Humana Press. https://doi.org/10.1007/978-1-59259-937-0_10
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DOI: https://doi.org/10.1007/978-1-59259-937-0_10
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