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Dopamine and Glutamate in Attention Deficit Hyperactivity Disorder

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Dopamine and Glutamate in Psychiatric Disorders

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Abstract

Attention deficit hyperactivity disorder (ADHD) is a complex condition, thought to have multiple subtypes lurking within a broad, behaviorally defined phenotype, making it difficult to identify specific biological causes of this syndrome. However, the evidence from studies conducted over the past decade suggests that dopamine (DA) plays a prominent role in the etiology and treatment of ADHD. Here we will start with consensus views that have emerged about ADHD at the behavioral, biological, and genetic levels of analysis. Then, we will summarize the evidence that links DA to ADHD.

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Author information

Authors and Affiliations

  1. Department of Pediatrics, University of California at Irvine, Irvine, CA

    James M. Swanson

  2. Brookhaven National Laboratory, Upton, NY

    Nora D. Volkow

  3. National Institute of Drug Abuse, Washington, DC

    Nora D. Volkow

  4. Department of Psychiatry, Mt. Sinai Medical School, New York, NY

    Jeffrey Newcorn

  5. Sackler Institute, Weill College of Medicine at Cornell University, New York, NY

    B. J. Casey

  6. Department of Biological Chemistry, University of California, Irvine, CA

    Robert Moyzis

  7. Department of Physiology and Pharmacology, Oregon Health and Science University, Portland, OR

    David K. Grandy

  8. Department of Psychology, University of Oregon, Eugene, OR

    Michael I. Posner

Authors
  1. James M. Swanson
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  2. Nora D. Volkow
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  3. Jeffrey Newcorn
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  4. B. J. Casey
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  5. Robert Moyzis
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  6. David K. Grandy
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  7. Michael I. Posner
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Editor information

Editors and Affiliations

  1. Department of Neuropharmacology Zoological Institute, University of Tübingen, Tübingen, Germany

    Werner J. Schmidt PhD

  2. Department of Psychiatry, New York University School of Medicine, New York, NY

    Maarten E. A. Reith PhD

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© 2005 Humana Press Inc., Totowa, NJ

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Swanson, J.M. et al. (2005). Dopamine and Glutamate in Attention Deficit Hyperactivity Disorder. In: Schmidt, W.J., Reith, M.E.A. (eds) Dopamine and Glutamate in Psychiatric Disorders. Humana Press. https://doi.org/10.1007/978-1-59259-852-6_13

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  • DOI: https://doi.org/10.1007/978-1-59259-852-6_13

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-325-1

  • Online ISBN: 978-1-59259-852-6

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