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Hepatocellular Cancer pp 185–198Cite as

Hepatic Resection for Hepatocellular Carcinoma

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Part of the book series: Current Clinical Oncology ((CCO))

Abstract

Hepatocellular carcinoma (HCC) is one of the most common tumors worldwide, with an estimated incidence of new cases ranging between 500,000 and 1 million annually. Historically, hepatic resection, either partial or total, has been considered to be the mainstay of surgical therapy. Liver transplantation, although known to have superior outcomes in patients with advanced concomitant cirrhosis, often is not feasible because the availability of hepatic allografts cannot meet demand; therefore, liver transplantation can be applied to only a small percentage of patients with HCC. To date, considerable knowledge and experience have been accumulated in resectional treatment for HCC, particularly in industrialized countries with a high incidence of viral hepatitis, and include: patient selection, improved preoperative diagnosis of tumor size and location in relation to intrahepatic vasculature, refined techniques for parenchymal dissection, improved understanding of the oncological behavior of HCC, and the influence of hepatic parenchymal inflammation on recurrence.

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Author information

Authors and Affiliations

  1. Department of Surgery, The Jikie University School of Medicine, Tokyo, Japan

    Katsuhiko Yanaga MD, PhD

  2. Department of Transplantation ad Digestive Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

    Sadayuki Okudaira MD, PhD

  3. Department of Surgery II, Nagasaki University School of Medicine, Nagasaki, Japan

    Takashi Kanematsu MD, PhD

  4. Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA

    J. Wallis Marsh MD, MBA

Authors
  1. Katsuhiko Yanaga MD, PhD
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  2. Sadayuki Okudaira MD, PhD
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  3. Takashi Kanematsu MD, PhD
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  4. J. Wallis Marsh MD, MBA
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Editor information

Editors and Affiliations

  1. Liver Cancer Center, Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA

    Brian I. Carr MD, FRCP, PhD

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© 2005 Humana Press Inc., Totowa, NJ

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Yanaga, K., Okudaira, S., Kanematsu, T., Marsh, J.W. (2005). Hepatic Resection for Hepatocellular Carcinoma. In: Carr, B.I. (eds) Hepatocellular Cancer. Current Clinical Oncology. Humana Press. https://doi.org/10.1007/978-1-59259-844-1_9

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  • DOI: https://doi.org/10.1007/978-1-59259-844-1_9

  • Publisher Name: Humana Press

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