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Hepatocellular Cancer pp 153–169Cite as

Percutaneous Ethanol and Acetic Acid Ablation of Hepatocellular Carcinoma

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Part of the book series: Current Clinical Oncology ((CCO))

Abstract

Hepatocellular carcinoma (HCC) is the most common primary hepatic tumor. Globally, HCC is one of the most common malignant visceral tumors (1,2), with more than 350,000 cases reported every year (1). Annual incidence rate in North and South America for HCC is 2–4 cases per 100,000 persons (1). The worldwide distribution of HCC is closely linked to the prevalence of hepatitis B infection. There is a 200-fold increased risk of HCC in adults who become hepatitis B virus (HBV) carriers during infancy as a result of vertical transmission from the infected mother (3). HCC in this population frequently occurs without coincident cirrhosis (in approx 50% cases) and at a younger age—often between 20 and 40 years (1). In contrast, cirrhosis is present in 85–90% cases of HCC in the Western population (low-incidence region), where HBV is not prevalent. The most common associations with HCC in this region are alcohol and chronic infection with hepatitis C virus (HCV) (1); rarely does it occur before age 60 years (1). Males outnumber females in the distribution of HCC in both the high- and low-incidence regions; the male/female ratio is 8:1 in the high-incidence population and 2:1 to 3:1 in the low-incidence population (1,2).

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Authors and Affiliations

  1. Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA

    Vibhu Kapoor MD & F. Leland Thaete MD

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  1. Vibhu Kapoor MD
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  2. F. Leland Thaete MD
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Editors and Affiliations

  1. Liver Cancer Center, Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA

    Brian I. Carr MD, FRCP, PhD

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© 2005 Humana Press Inc., Totowa, NJ

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Kapoor, V., Thaete, F.L. (2005). Percutaneous Ethanol and Acetic Acid Ablation of Hepatocellular Carcinoma. In: Carr, B.I. (eds) Hepatocellular Cancer. Current Clinical Oncology. Humana Press. https://doi.org/10.1007/978-1-59259-844-1_7

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  • DOI: https://doi.org/10.1007/978-1-59259-844-1_7

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-125-7

  • Online ISBN: 978-1-59259-844-1

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