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The GMO Handbook pp 243–262Cite as

Gene Silencing in Plants

Nature’s Defense

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Abstract

Plants have evolved mechanisms to limit viral infections and genomic damage that can occur by the invasion, proliferation, and expression of viruses and mobile genetic elements such as retroelements and transposons (1). Up to 95% of a plant’s genome is comprised of repetitive elements. The mechanisms involved with limiting expression of this “junk” deoxyribonucleic acid (DNA) have significantly hindered progress in agricultural biotechnology because DNA carrying genes of interest is often subjected to the same protective surveillance mechanisms and their expression shut down. This phenomenon, known as gene silencing, can occur immediately following integration of transgenes or over several generations. Gene silencing can affect some or all plants derived from a transgenic event, and expression can be partially or fully turned off.

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Authors
  1. W. Michael Ainley
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  2. Siva P. Kumpatla
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  1. Dow AgroSciences, Indianapolis, IN, USA

    Sarad R. Parekh PhD

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Ainley, W.M., Kumpatla, S.P. (2004). Gene Silencing in Plants. In: Parekh, S.R. (eds) The GMO Handbook. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-801-4_9

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