Hereditary Prostate Cancer and Genetic Risk

  • Phillippa J. Neville
  • Graham Casey
  • John S. Witte
Part of the Current Clinical Urology book series (CCU)


Prostate cancer is the most common noncutaneous malignancy and the second leading cause of cancer-related deaths among men in the United States; in 2002, approx 189,000 men were diagnosed with—and 30,200 men died from—this disease (1). Moreover, prostate cancer is one of the most familial of common cancers. In comparison with men who have no family history of prostate cancer, those who have a first-degree relative diagnosed with this disease have a two—fourfold greater risk, and those with three or more first-degree relatives with prostate cancer have an approx 11-fold increased risk (2–7).


Prostate Cancer BRCA2 Mutation Natl Cancer Inst Prostate Cancer Risk Hereditary Prostate Cancer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2004

Authors and Affiliations

  • Phillippa J. Neville
  • Graham Casey
  • John S. Witte

There are no affiliations available

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