Bone-Targeted Therapy for Prostate Cancer

  • Navjeet Gandhok
  • Oliver Sartor
Part of the Current Clinical Urology book series (CCU)


Both prostate cancer and treatments for prostate cancer have potentially harmful effects on bone. Prostate cancer reliably metastasizes to bone in its advanced stages, and these metastatic deposits have a variety of deleterious effects on patients including pain and pathologic fractures. In addition, commonly utilized androgen deprivation strategies used in prostate cancer treatment reduce bone mineral density, which in turn can lead to osteopenia or osteoporosis with its attendant risks. Thus, a relatively unique series of relationships exists in prostate cancer patients among the bone, the cancer, and commonly administered treatments.


Prostate Cancer Bone Mineral Density Bone Metastasis Prostate Cancer Cell Zoledronic Acid 
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© Springer Science+Business Media New York 2004

Authors and Affiliations

  • Navjeet Gandhok
  • Oliver Sartor

There are no affiliations available

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