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Nutrition and Bone Health in Children and Adolescents

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Book cover Nutrition and Bone Health

Part of the book series: Nutrition and Health ((NH))

Abstract

Adult skeletons evolved from a single cell with a programmed system of constraints on development and mineralization which is under strict genetic control. It has been speculated that genetics contributes about 80% of the variance in bone mass and the remaining 20% is affected by one’s environment, although the exact contribution of each major determinant of bone mass is unknown. Research data support the hypothesis that peak bone size, bone mass, and to a lesser extent the distribution of bone tissue within the bone as an organ (volumetric bone density) in young individuals are strongly influenced by genetic information by both parents (Fig. 1) (1). This indirectly suggests that bone candidate genes responsible for bone modeling drifts along the longitudinal and periosteal axes in interaction with nutritional factors and physical exercise have an important impact on skeletal development and peak bone mass.

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Authors
  1. Velimir Matkovic
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  2. Nancy Badenhop-Stevens
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  3. Eun-Jeong Ha
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  4. Zeljka Crncevic-Orlic
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  5. Albert Clairmont
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Editor information

Editors and Affiliations

  1. Department of Medicine, Dermatology, Physiology, and Biophysics, Boston University School of Medicine, Boston, MA, USA

    Michael F. Holick PhD, MD

  2. Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA

    Bess Dawson-Hughes MD

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© 2004 Springer Science+Business Media New York

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Matkovic, V., Badenhop-Stevens, N., Ha, EJ., Crncevic-Orlic, Z., Clairmont, A. (2004). Nutrition and Bone Health in Children and Adolescents. In: Holick, M.F., Dawson-Hughes, B. (eds) Nutrition and Bone Health. Nutrition and Health. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-740-6_11

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  • DOI: https://doi.org/10.1007/978-1-59259-740-6_11

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-451-7

  • Online ISBN: 978-1-59259-740-6

  • eBook Packages: Springer Book Archive

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