Abstract
Each year, malaria accounts for more deaths worldwide than any other parasitic disease, with mortality estimates of between 1.5 and 2.7 million (1). Malaria not only is associated with huge morbidity and mortality, but also it hampers economic growth, trapping endemic countries in a cycle of poverty and disease (2–4).The main disease burden is in Africa, and there is evidence that the incidence of malaria is increasing, as is childhood mortality. This may be directly attributed to the emergence and spread of chloroquine-resistant strains (5). Faced with this disaster and the rapidly declining efficacy of sulfadoxine-pyrimethamine in East African countries, national malaria control programs are struggling with the decision of which treatment to recommend next (6,7).
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Ashley, E., Nosten, F. (2004). Management of Multiple Drug-Resistant Malaria. In: Gillespie, S.H. (eds) Management of Multiple Drug-Resistant Infections. Infectious Disease. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-738-3_18
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DOI: https://doi.org/10.1007/978-1-59259-738-3_18
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