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Soluble Signals and Insoluble Substrata

Novel Molecular Cues Instructing the Induction of Bone

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The Skeleton

Abstract

The repair and regeneration of bone is a complex process that is temporally and spatially regulated by soluble and insoluble signals (1). The initiation of bone formation during embryonic development and postnatal osteogenesis involves a complex cascade of molecular and morphogenetic processes that ultimately lead to the architectural sculpturing of precisely organized multicellular structures.

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Authors
  1. Ugo Ripamonti
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  2. Nathaniel L. Ramoshebi
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  3. Janet Patton
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  4. Thato Matsaba
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  5. June Teare
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  6. Louise Renton
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Editors and Affiliations

  1. Developmental Biology Branch, Reproductive Toxicology Division, The National Health and Environmental Effects Research Laboratory, Office of Research Development, United States Environmental Protection Agency, Research Triangle Park, NC, USA

    Edward J. Massaro  & John M. Rogers  & 

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Ripamonti, U., Ramoshebi, N.L., Patton, J., Matsaba, T., Teare, J., Renton, L. (2004). Soluble Signals and Insoluble Substrata. In: Massaro, E.J., Rogers, J.M. (eds) The Skeleton. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-736-9_15

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  • DOI: https://doi.org/10.1007/978-1-59259-736-9_15

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-427-2

  • Online ISBN: 978-1-59259-736-9

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