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Adult Stem Cell Plasticity

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Adult Stem Cells

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Abstract

Although modern medicine has provided the ability to cure infections and malignancy, the ability to repair damaged organs is less advanced. Solid organ transplantation has been performed successfully, but is fraught with problems such as rejection, infection, and secondary malignancy from immunosuppression. Organ shortages create ethical issues with respect to the equitable distribution of donated tissues. Regenerative medicine, the field devoted to rebuilding damaged organs from stem cells, may provide alternatives to solid organ transplantation. However, the field of regenerative medicine is in its infancy. The potential sources of the tissues to regenerate organs include cloned cells, embryonic or fetal stem cells, or adult stem cells. Although each of these sources of stem cells has potential biological advantages and disadvantages, ethical and legal concerns have been raised by cloning (1–4) and the use of embryonic and fetal stem cells (5).

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Authors
  1. William B. Slayton
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  2. Gerald J. Spangrude
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Editors and Affiliations

  1. Hormones, Growth, and Development Program, Ottawa Health Research Institute, Ottawa Hospital, Ottawa, Ontario, Canada

    Kursad Turksen

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© 2004 Springer Science+Business Media New York

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Slayton, W.B., Spangrude, G.J. (2004). Adult Stem Cell Plasticity. In: Turksen, K. (eds) Adult Stem Cells. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-732-1_1

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  • DOI: https://doi.org/10.1007/978-1-59259-732-1_1

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-392-3

  • Online ISBN: 978-1-59259-732-1

  • eBook Packages: Springer Book Archive

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