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Early Clinical Intervention and Prevention in Schizophrenia pp 75–91Cite as

The Nature of the Prodrome in Schizophrenia

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Abstract

In 1927, Harry Stack Sullivan (1) wrote about the onset of schizophrenia stating the following:

The psychiatrist sees too many end states and deals professionally with too few of the pre-psychotic.... With this in mind, it would seem as if we should lay great stress on the prompt investigation of failing adjustment, rather than, as is so often the case, wait and see what happens.... I feel certain that many incipient cases might be arrested before the efficient contact with reality is completely suspended, and a long stay in institutions made necessary. (p. 135)

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References

  1. Sullivan HS. The onset of schizophrenia. Am J Psychiatry 1994; 151(6):135–139.

    Google Scholar 

  2. McGlashan TH. A selective review of recent North American long-term follow-up studies of schizophrenia. Schizophr Bull 1988; 14(4):515–542.

    CAS  PubMed  Google Scholar 

  3. Lieberman JA, Kinon BJ, Loebel AD. Dopaminergic mechanisms of idopathic and drug induced psychosis. Schizophr Bull 1990; 16(1):97–110.

    CAS  PubMed  Google Scholar 

  4. Wyatt RJ. Early intervention for schizophrenia: can the course of the illness be altered? Biol Psychiatry 1995; 38(1):1–3.

    Article  CAS  PubMed  Google Scholar 

  5. Loebel AD, Lieberman JA, Alvir JMJ, Mayerhoff DI, Deisler SH, Szymanski SR. Duration of psychosis and outcome in first episode schizophrenia. Am J Psychiatry 1992; 149:1183–1188.

    CAS  PubMed  Google Scholar 

  6. McGlashan TH, Johannessen JO. Early detection and intervention with schizophrenia: rationale. Schizophr Bull 1996; 22(2):201–222.

    Article  CAS  PubMed  Google Scholar 

  7. McGlashan, TH. Early detection and intervention in schizophrenia: editor’s introduction. Schizophr Bull 1996; 22(2):197–199.

    Article  CAS  PubMed  Google Scholar 

  8. Meehl P. Schizotaxia, schizotypy, schizophrenia. Am Psychol 1962; 17:827–838.

    Article  Google Scholar 

  9. Tiernari P, Wynne L, Moring J, et al. The Finnish adoptive family study of schizophrenia: implications for family research. Br J Psychiatry 1994; 164(Suppl 23):20–26.

    Google Scholar 

  10. Olin SS, Mednick SA. Risk factors of psychosis: identifying vulnerable populations premorbidly. Schizophr Bull 1996; 22(2):223–240.

    Article  CAS  PubMed  Google Scholar 

  11. Sameroff A, Seifer R, Zax M, Barocas R. Early indicators of developmental risk: Rochester Longitudinal Study. Schizophr Bull 1987; 13(3):383–394.

    CAS  PubMed  Google Scholar 

  12. Jones P, Rodgeres B, Murray R, Marmot M. Child developmental risk factors for adult schizophrenia in the British 1946 birth cohort. Lancet 1994; 344:1398–1402.

    Article  CAS  PubMed  Google Scholar 

  13. Jones P, van Oss H. Predicting schizophrenia in teenagers pessimistic results from the British 1946 birth cohort. Conference on Schizophrenia Research, Colorado Springs, CO, April 1997.

    Google Scholar 

  14. Jones P, Croudace J. Predicting schizophrenia from teachers’ reports of behaviour: results from a general population birth cohort. In: Miller T, et al., eds. Early Intervention in Psychotic Disorders. Dordrecht, Netherlands: Kluwer Academic, 2001:1–28.

    Chapter  Google Scholar 

  15. Davidson M, Reichenberg MA, Rabinowitz J, Weiser M, Kaplan Z, Mark M. Behavioral and intellectual markers for schizophrenia in apparently healthy male adolescents. Am J Psychiatry 1999; 156(9):1328–1335.

    CAS  PubMed  Google Scholar 

  16. Yung AR, McGorry PD. The prodromal phase of first-episode psychosis: past and current conceptualizations. Schizophr Bull 1996; 22(2):353–370.

    Article  CAS  PubMed  Google Scholar 

  17. McGlashan TH, Levy ST, Carpenter W. Integration and sealing over: clinically distinct recovery styles from schizophrenia. Arch Gen Psychiatry 1975; 32:1269–1272.

    Article  CAS  PubMed  Google Scholar 

  18. Johnstone EC, Crow TJ, Johnson AL, MacMillan JF. The Northwick Park Study of first episode schizophrenia: I. Presentation of the illness and problems relating to admission. Br J Psychiatry 1986; 148:115–120.

    Article  CAS  PubMed  Google Scholar 

  19. Chapman JP, Day D, Burstein A. The process-reactive distinction and prognosis in schizophrenia. J Nery Ment Dis 1961; 133:383–391.

    Article  CAS  Google Scholar 

  20. Fenton WS, McGlashan TH. The prognostic scale for chronic schizophrenia. Schizophr Bull 1987; 13(2):277–286.

    CAS  PubMed  Google Scholar 

  21. Bowers MB. The onset of psychosis: a diary account. Psychiatry 1965; 28:346–358.

    CAS  PubMed  Google Scholar 

  22. Bowers MB. Pathogenesis of acute schizophrenia. Arch Gen Psychiatry 1968; 19:348–355.

    Article  PubMed  Google Scholar 

  23. Henrichs DW, Carpenter WT. Prospective study of prodromal symptoms in schizophrenic relapse. Am J Psychiatry 1985; 142:371–373.

    Google Scholar 

  24. Cameron DE. Early schizophrenia. Am J Psychiatry 1938; 95:567–578.

    Google Scholar 

  25. Chapman JP. The early symptoms of schizophrenia. Br J Psychiatry 1966; 112:225–251.

    Article  CAS  PubMed  Google Scholar 

  26. Huber G, Gross G, Schiittler R, Linz M. Longitudinal studies of schizophrenic patients. Schizophr Bull 1980; 6(4):592–605.

    CAS  PubMed  Google Scholar 

  27. Koehler K, Sauer H. Huber’s basic symptoms: another approach to negative psychopathology in schizophrenia. Compr Psychiatry 1984; 25:174–182.

    Article  CAS  PubMed  Google Scholar 

  28. McGorry RD, Singh BS. Schizophrenia: risk and possibility of prevention. In: Raphael B, Burrows GD, eds. Handbook of Preventive Psychiatry. Amsterdam: Elsevier, 1995:492–514.

    Google Scholar 

  29. Häfner H, Maurer K. The prodromal phase of psychosis. In: Miller T, et al., eds. Early Intervention in Psychotic Disorders. Dordrecht, Netherlands: Kluwer Academic, 2001:71–100.

    Chapter  Google Scholar 

  30. Maurer K, Häfner H. Methodological aspects of onset assessment in schizophrenia. Schizophr Res 1995; 15:265–276.

    Article  CAS  PubMed  Google Scholar 

  31. MØller P, Husby R. The initial prodrome in schizophrenia: searching for naturalistic core dimensions of experience and behavior. Schizophr Bull 2000; 26(1):217–232.

    Article  PubMed  Google Scholar 

  32. MØller P. First-episode schizophrenia: do grandiosity, disorganization, and acute initial development reduce duration of untreated psychosis? An exploratory naturalistic case study. Compr Psychiatry 2000; 41(3):184–190.

    Article  PubMed  Google Scholar 

  33. Klosterkötter J, Helmich M, Steinmeyer EM, Scultze-Lutter F. Diagnosing schizophrenia in the initial prodromal phase. Arch Gen Psychiatry 2001; 58(2):158–164.

    Article  PubMed  Google Scholar 

  34. Gross G. The “basic symptoms” of schizophrenia. Br J Psychiatry 1989; Suppl 7:21–25.

    Google Scholar 

  35. Yung AR, McGorry PD, McFarlane CA, Jackson HJ, Patton GC, Rakker A Monitoring and care of young people at incipient risk of psychosis. Schizophr Bull 1996; 22(2):283–303.

    Article  CAS  PubMed  Google Scholar 

  36. Miller TJ, McGlashan TH, Woods SW, et al. Symptom assessment in schizophrenic prodromal states. Psychiatr Q 1999; 70(4):273–287.

    Article  CAS  PubMed  Google Scholar 

  37. McGlashan TH, Miller TJ, Woods SW, Hoffman RE, Davidson L. Instrument for the assessment of prodromal symptoms and states. In: Miller T, et al., eds. Early Intervention in Psychotic Disorders. Dordrecht, Netherlands: Kluwer Academic, 2001:135–149.

    Chapter  Google Scholar 

  38. Falloon IRH. Early intervention for first episodes of schizophrenia: a preliminary exploration. Psychiatry 1992; 55:4–15.

    CAS  PubMed  Google Scholar 

  39. Philips L, McGorry PD. The development of preventive interventions for early psychosis. Paper presented at the Second International Conference on Early Psychosis, New York, April 2, 2000.

    Google Scholar 

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Authors
  1. Jaak Rakfeldt PhD
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  2. Thomas H. McGlashan MD
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Editor information

Editors and Affiliations

  1. Harvard Institute of Psychiatric Epidemiology and Genetics, Boston, MA, USA

    William S. Stone PhD , Stephen V. Faraone PhD  & Ming T. Tsuang MD, PhD, DSc ,  & 

  2. Harvard Medical School Department of Psychiatry at Massachusetts Mental Health Center, Boston, MA, USA

    William S. Stone PhD

  3. Harvard Medical School Department of Psychiatry at Massachusetts General Hospital, Boston, MA, USA

    Stephen V. Faraone PhD

  4. Harvard Medical School Departments of Psychiatry at Massachusetts Mental Health Center and Massachusetts General Hospital, Boston, MA, USA

    Ming T. Tsuang MD, PhD, DSc

  5. Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA

    Ming T. Tsuang MD, PhD, DSc

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© 2004 Humana Press Inc., Totowa, NJ

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Rakfeldt, J., McGlashan, T.H. (2004). The Nature of the Prodrome in Schizophrenia. In: Stone, W.S., Faraone, S.V., Tsuang, M.T. (eds) Early Clinical Intervention and Prevention in Schizophrenia. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-729-1_4

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  • DOI: https://doi.org/10.1007/978-1-59259-729-1_4

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4684-9833-2

  • Online ISBN: 978-1-59259-729-1

  • eBook Packages: Springer Book Archive

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