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Obstetric Risk Factors for Schizophrenia and Their Relationship to Genetic Predisposition

Following Ariadne’s Double-Stranded Thread Through Early Development

  • Chapter
Early Clinical Intervention and Prevention in Schizophrenia

Abstract

The literature on early life environmental risk factors for schizophrenia is a labyrinth of enormous extent, and it is growing. A literature search on obstetric and pregnancy complications and schizophrenia yields more than 1000 papers. In the arduous attempt to provide a compass, we have been struck by the tension between genes and early environment that is present throughout this literature. We do not promise to find the exit to the labyrinth, we only hope to show that following both threads will be necessary to start to understand the pathophysiology of the illness.

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Marenco, S., Weinberger, D.R. (2004). Obstetric Risk Factors for Schizophrenia and Their Relationship to Genetic Predisposition. In: Stone, W.S., Faraone, S.V., Tsuang, M.T. (eds) Early Clinical Intervention and Prevention in Schizophrenia. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-729-1_3

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