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Physical Activity and Insulin Resistance in Man

  • Chapter
Insulin Resistance

Part of the book series: Contemporary Endocrinology ((COE,volume 12))

Abstract

After both acute exercise and physical training, i.e., regularly performed exercise, increased glucose tolerance or unchanged glucose tolerance in the face of lower plasma insulin concentrations may be seen during oral (OGTT) and intravenous (IVGTT) glucose loading (85,89,116,148). Conversely, physical inactivity during bed rest or resulting from spinal cord injury decreases glucose tolerance in the face of increased insulin concentrations (39,88,107). The deterioration in glucose tolerance during bed rest can be diminished by exercise (39,88). These findings indicate a direct relationship between physical activity and insulin action and also suggest an inverse relationship between physical activity and glucose induced insulin secretion.

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Authors
  1. Flemming Dela MD, DMSC
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  2. Kári Mikines MD, DMSC
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  3. Henrik Galbo MD, DMSC
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Editors and Affiliations

  1. Shaman Pharmaceuticals, Inc., South San Francisco, CA, USA

    Gerald M. Reaven MD

  2. Stanford University School of Medicine, Stanford, CA, USA

    Gerald M. Reaven MD

  3. Stanford University School of Medicine, Stanford, CA, USA

    Ami Laws MD

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Dela, F., Mikines, K., Galbo, H. (1999). Physical Activity and Insulin Resistance in Man. In: Reaven, G.M., Laws, A. (eds) Insulin Resistance. Contemporary Endocrinology, vol 12. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-716-1_6

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  • DOI: https://doi.org/10.1007/978-1-59259-716-1_6

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-086-1

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