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IGF Deficiency

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The IGF System

Part of the book series: Contemporary Endocrinology ((COE,volume 17))

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Abstract

The molecular biology and physiology of the insulin-like growth factor (IGF) system are complex, as detailed in the earlier chapters of this book, and there are consequently many potential mechanisms of IGF deficiency. Broadly, there may be primary IGF deficiency, in which the defect lies in IGF synthesis, or secondary IGF deficiency, in which low levels of IGF arise as a consequence of a deficiency in the pathway leading to IGF production (Table 1).

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Authors
  1. Katie A. Woods MD, MRCP
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  2. Martin O. Savage MA, MD, FRCP
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Editors and Affiliations

  1. Department of Pediatrics, School of Medicine, Oregon Health Sciences University, Portland, OR, USA

    Ron G. Rosenfeld MD

  2. Oregon Health Sciences University, Portland, OR, USA

    Charles T. Roberts Jr. PhD

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Woods, K.A., Savage, M.O. (1999). IGF Deficiency. In: Rosenfeld, R.G., Roberts, C.T. (eds) The IGF System. Contemporary Endocrinology, vol 17. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-712-3_27

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  • DOI: https://doi.org/10.1007/978-1-59259-712-3_27

  • Publisher Name: Humana Press, Totowa, NJ

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