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Biotherapeutic Agents and Adult Diarrhea

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Biotherapeutic Agents and Infectious Diseases

Abstract

Diarrhea is a symptom characterized by the frequent passage of liquid stools with an increased excretion of water and electrolytes. Development of acute diarrhea in adults is usually owing to ingestion and subsequent colonization of the intestine by viruses or enteric pathogens. Resulting dysfunctions in the intestinal microflora and potential toxin production are among the mechanisms leading to altered intestinal mucosal function and diarrhea. An example of the chain of events is presented in Fig. 1. Other types of diarrhea can be caused by dysfunctions in the intestinal barrier mechanisms resulting from antimicrobial agents, radiation therapy, chemotherapy, and dietary factors, such as lactose intolerance and other intolerances.

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Authors
  1. S. Salminen
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  2. E. Isolauri
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  3. E. Salminen
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Editor information

Editors and Affiliations

  1. Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, WA, USA

    Gary W. Elmer  & Lynne V. McFarland  & 

  2. Biocodex Inc., Seattle, WA, USA

    Lynne V. McFarland

  3. Department of Medicine, Harborview Medical Center, University of Washington, Seattle, WA, USA

    Christina M. Surawicz

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Salminen, S., Isolauri, E., Salminen, E. (1999). Biotherapeutic Agents and Adult Diarrhea. In: Elmer, G.W., McFarland, L.V., Surawicz, C.M. (eds) Biotherapeutic Agents and Infectious Diseases. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-711-6_9

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  • DOI: https://doi.org/10.1007/978-1-59259-711-6_9

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4757-4652-5

  • Online ISBN: 978-1-59259-711-6

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