Skip to main content

Marihuana Smoking, a Possible Carcinogen or Cocarcinogen

  • Chapter
Marihuana and Medicine
  • 677 Accesses

Abstract

Marihuana smoking may act as a carcinogen or co-carcinogen. It contains several proven carcinogens such as nitrosoamine and benzene, and is known to damage the respiratory epithelium, including the nasopharynx. There is also a proven decrease in cellular and humoral immunity. These facts, coupled with reports in the literature of multiple cases of cancer of the respiratory tract in the young with the average age at onset of 26 years, highlight this hazard. The AIDS population (whose life-span is now being prolonged) are the most susceptible to this potential effect of marihuana smoking.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Hoffman, D., Brunnemann, K. D., Gori, G. S., and Wynder, E. L. (1975) On the carcinogenicity of marihuana smoke. Recent Adv. Phytochem. 9, 63–81.

    Article  Google Scholar 

  2. Wehner, F. C., Van Rensurg, S. J., and Theil, P. F. (1980) Mutagenicity of marihuana and Transkei tobacco smokes condensates in the Salmonellalmicrosome assay. Muta. Res. 77, 135–142.

    Article  CAS  Google Scholar 

  3. Donald, P. J. (1986) Marihuana smoking—possible cause of head and neck carcinoma in young patient. Otlaryngol. Head Neck Surg. 94, 517–521.

    CAS  Google Scholar 

  4. Tashkin, D. O., Coulson, A. H., Clark, V. A., Simmons, M., Bourque, L. B., Duann, S., Spivey, G. H., and Gong, H. (1987) Respiratory symptoms and lung function in habitual, heavy smokers of tobacco alone, and nonsmokers. Am. Rev. Respir. Dsi. 135 209–216.

    CAS  Google Scholar 

  5. Taskin, D. P. (1997) Potential respiratory and infectious comlications of medical marihuana: suggested monitoring procedures. Presented by D. P. Tashkin at the 1997 Symposium on the Cannabinoids of the International Cannabinoid Research Society, Stone Mountain, GA, June, 1997, International Cannabinoid Research Society Program and Abstracts, p. 89.

    Google Scholar 

  6. Taylor, F. M., III. (1988) Marihuana as a potential respiratory tract carcinogen. A retrospective analysis of a community hospital population. S. Med. J. 81, 1213–1216.

    Article  Google Scholar 

  7. Sridhar, K. S., Raub, W. A., and Weatherby, N. L., et al. (1994) Possiblerole of marihuana smoking as a carcinogen in the development of lung cancer at a young age. J. Psychoactive Drugs 26 285–288.

    Article  PubMed  CAS  Google Scholar 

  8. American Thoracic Society. (1975) Position paper: marihuana and the lungs. Am. Thoracic. Soc. News Spring, 7.

    Google Scholar 

  9. Leuchtenberger, C., Leuchtenberger. R., and Ritter, U. (1973) Effects f marihuana and tobacco smoke on DNA and chromosomal compliment in human lung expants. Nature 242, 403–404.

    CAS  Google Scholar 

  10. Peterson, B. H., Lemberger, L. Graham, J., and Dalton, B. (1975) Alternations in the cellular-mediated immune responsiveness of chronic marihuana smokers. Psychopharmacol. Commun. 1,, 67–74.

    Google Scholar 

  11. Nahas, G. G., Desoize, B., Armand, J. R, Hsu., J., and Morishima, A. (1975) Natural canabinoids: apparent depression of nucleic acids and protein synthesis and cultures of human lymphocytes. In: (Szara, S. and Braude, X, eds.) Raven, New York, pp. 177–188.

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1999 Springer Science+Business Media New York

About this chapter

Cite this chapter

Hyman, G. (1999). Marihuana Smoking, a Possible Carcinogen or Cocarcinogen. In: Nahas, G.G., Sutin, K.M., Harvey, D., Agurell, S., Pace, N., Cancro, R. (eds) Marihuana and Medicine. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-710-9_29

Download citation

  • DOI: https://doi.org/10.1007/978-1-59259-710-9_29

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4757-5717-0

  • Online ISBN: 978-1-59259-710-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics