Abstract
The intensity and persistence of drug-craving behavior in the human addict suggests that the difficulty people experience in overcoming addiction is far more complex than a simple lack of will power. Drugs of abuse, such as cocaine, also appear to cause long-term physical alterations in the brain that may make it very difficult for them to merely change their minds about using drugs. In a discussion of these kinds of physical alterations at the molecular level, there is a great deal of detail and jargon. Added detail and extra jargon were saved for the figure legends and bracketed comments and can be ignored by those uninterested in the details.
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Hope, B.T. (1999). Cocaine and a Mechanism for Long-Term Changes in Gene Expression. In: Nahas, G.G., Sutin, K.M., Harvey, D., Agurell, S., Pace, N., Cancro, R. (eds) Marihuana and Medicine. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-710-9_21
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DOI: https://doi.org/10.1007/978-1-59259-710-9_21
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