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Nucleotides

  • Chapter
Nutrition and Immunology

Abstract

There is no overriding biochemical reason why dietary nucleotides should be considered as essential nutrients. Pathways for their synthesis or salvage are (with one exception) present in every tissue and interorgan traffic should provide sufficient substrate for any tissue with increased requirements for DNA and RNA turnover. Indeed, dietary nucleotides have had a rather negative implication because of their role in the etiology of gout. Nevertheless, this model of metabolic complacency has been punctured by successive research publications which suggest that dietary nucleotide deficiency may impair liver, heart, intestine, and immune function.

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Authors
  1. George K. Grimble
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  2. Olwyn M. R. Westwood
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Editors and Affiliations

  1. Division of Rheumatology/Allergy and Clinical Immunology, Department of Internal Medicine, University of California at Davis, Davis, CA, USA

    M. Eric Gershwin MD

  2. Department of Food Science and Technology, University of California at Davis, Davis, CA, USA

    J. Bruce German PhD

  3. Department of Nutrition, University of California at Davis, Davis, CA, USA

    Carl L. Keen PhD

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© 2000 Springer Science+Business Media New York

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Grimble, G.K., Westwood, O.M.R. (2000). Nucleotides. In: Gershwin, M.E., German, J.B., Keen, C.L. (eds) Nutrition and Immunology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-709-3_11

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  • DOI: https://doi.org/10.1007/978-1-59259-709-3_11

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-148-6

  • Online ISBN: 978-1-59259-709-3

  • eBook Packages: Springer Book Archive

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