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Basic Elements of Molecular Biology

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Biopharmaceutical Drug Design and Development

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Abstract

Molecular biology involves the study of gene structure, function, and manipulation. Molecular biotechnology is being applied to the understanding of pathogenesis, susceptibility, diagnosis, and, more recently, the treatment of diseases in all branches of medicine. The purpose of this chapter is to lay the foundation that will enable a nonmolecular biologist to negotiate the following chapters successfully. This introduction to the basic principles and terminology of molecular biology should provide the necessary background information for more specialized applications of molecular biotechnology.

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Further Readings

  • Cooper, G. M. (1997) The Cell: AMolecularApproach, ASM, Washington, DC

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  • Crick, F. H. C., Barnett, L., Brenner, S., and Watts-Tobin, J. (1962) General nature of the genetic code for proteins. Nature 192, 1227–1232.

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  • Darnell, J., Lodish, H., and Baltimore, D. (1986) Molecular Cell Biology, Scien-tific American, New York.

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  • Glick, B. R. and Pasternak, J. J. (1994) Molecular Biotechnology: Principles and Applications of Recombinant DNA, ASM, Washington, DC.

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  • Kreuzer, H. and Massey, A. (1996) Recombinant DNA and Biotechnology, ASM, Washington, DC.

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  • Lewin, B. (1990) Gene IV, John Wiley, New York.

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  • Nirenberg, M. and Leder, P. (1964) RNA codewords and protein synthesis. Science 145, 1399–1407.

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  • Old, R. W. and Primrose, S. B. (1994) Principles of Gene Manipulation: An Intro-duction to Genetic Engineering, 5th ed., Blackwell Science, Oxford, UK.

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  • Watson, J. D., Gilman, M., Witkowski, J., and Zoller, M. (1992) Recombinant DNA, 2nd ed., W. H. Freeman, New York.

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Authors
  1. Yongyut Rojanasakul
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Editor information

Editors and Affiliations

  1. Department of Pharmacy and Pharmaceutics, Virginia Commonwealth University, Richmond, VA, USA

    Susanna Wu-Pong PhD

  2. School of Pharmacy, West Virginia University, Morgantown, WV, USA

    Yongyut Rojanasakul PhD

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© 1999 Springer Science+Business Media New York

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Rojanasakul, Y. (1999). Basic Elements of Molecular Biology. In: Wu-Pong, S., Rojanasakul, Y. (eds) Biopharmaceutical Drug Design and Development. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-705-5_2

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  • DOI: https://doi.org/10.1007/978-1-59259-705-5_2

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4757-4644-0

  • Online ISBN: 978-1-59259-705-5

  • eBook Packages: Springer Book Archive

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