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Chemokines and Hematopoiesis

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Chemokines and Cancer

Part of the book series: Contemporary Cancer Research ((CCR))

Abstract

Hematopoiesis refers to the production of blood cells, a dynamic process that supplies and replenishes the mature blood cell elements necessary to sustain life (1–4). The homeostatic mechanisms that maintain blood cell levels within defined limits under normal conditions and the accelerated production of these cells under stress-induced conditions, such as infection or after cytotoxic drug therapy, reflect a balance between cell-cell and cytokine-cell interactions.

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Authors
  1. Hal E. Broxmeyer
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  2. Chang H. Kim
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Editors and Affiliations

  1. Department of Adult Oncology, Dana-Farber Cancer Institute, Boston, MA, USA

    Barrett J. Rollins MD, PhD

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Broxmeyer, H.E., Kim, C.H. (1999). Chemokines and Hematopoiesis. In: Rollins, B.J. (eds) Chemokines and Cancer. Contemporary Cancer Research. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-701-7_15

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  • DOI: https://doi.org/10.1007/978-1-59259-701-7_15

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4757-4760-7

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