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Intraoperative Irradiation with Electron-Beam or High-Dose-Rate Brachytherapy

Methodological Comparisons

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Intraoperative Irradiation

Part of the book series: Current Clinical Oncology ((CCO))

Abstract

Intraoperative irradiation (IORT) refers to delivery of a single dose of irradiation to a surgically exposed tumor or tumor bed while the normal tissues are protected from the irradiation either by retracting the mobilized tissue or by shielding the anatomically fixed tissues. IORT has traditionally been performed by using an electron beam as the source of irradiation.

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References

  1. Nag S and Orton C. Development of intraoperative high dose rate brachytherapy for treatment of resected tumor beds in anesthetized patients, Endcurieth Hyperth. Oncol., 9 (1993) 187–193.

    Google Scholar 

  2. Nag S, Martinez-Monge R, and Gupta N. Intraoperative radiation therapy using electron-beam and highdose-rate brachytherapy, Cancer J., 10 (1997) 94–101.

    Google Scholar 

  3. Harrison LB, Enker WE, and Anderson LL. High dose rate intraoperative radiation therapy for colorectal cancer. Part I, Oncology, 9 (1995) 679–684.

    Google Scholar 

  4. Nag S, Lukas P, Thomas DS, and Harrison L. Intraoperative high dose rate remote brachytherapy, In Nag S (ed.), High Dose Rate Brachytherapy: A Textbook, Futura Publishing, Armonk, NY, 1994, p. 427–445.

    Google Scholar 

  5. Lukas P, Stepan R, Ries G, et al. A new modality for intraoperative radiation therapy with a high-doserate-afterloading unit, Radiology, 181 (1991) 251.

    Google Scholar 

  6. McCullough E and Anderson JA. The dosimetric properties of an applicator system for intraoperative electron beam therapy utilizing a Clinic-8 accelerator, Med. Phys., 9 (1982) 261–268.

    Article  PubMed  CAS  Google Scholar 

  7. Gunderson LL, Nelson H, Martenson JA, et al. Locally advanced primary colorectal cancer. Intraoperative electron and external beam irradiation ± 5FU, Int. J. Radiat. Oncol. Biol. Phys., 37 (1997) 601–614.

    Article  PubMed  CAS  Google Scholar 

  8. Dritschilo A, Harter KW, Thomas D, et al. Intraoperative radiation therapy of hepatic metastases: technical aspects and report of a pilot study, Int. J. Radiat. Oncol. Biol. Phys., 14 (1988) 1007–1011.

    Article  PubMed  CAS  Google Scholar 

  9. Thomas DS, Nauta RJ, Rodgers JE, et al. Intraoperative high-dose rate interstitial irradiation of hepatic metastases from colorectal carcinoma. Results of a phase I-II trial, Cancer, 71 (1993) 1977–1981.

    Article  PubMed  CAS  Google Scholar 

  10. Nag S. Radiotherapy and brachytherapy for recurrent colorectal cancer. Sem. Surg. Oncol., 7 (1991) 177–180.

    Article  CAS  Google Scholar 

  11. Erickson B and Nag S. Bile duct and liver. In Nag S (ed.), Principles and Practice of Brachytherapy, Futura Publishing, Armonk, NY, 1997, pp. 367–391.

    Google Scholar 

  12. Calvo FA, Azinovic J, and Escude LL. Intraoperative radiotherapy in cancer management. Appl. Radiol., 27 (1992) 19–23.

    Google Scholar 

  13. Calvo FA, Santos JA, and Lozano MA. Intraoperative radiotherapy: methodological development and early clinical experience, Oncologia, 20 (1997) 435–443.

    Article  Google Scholar 

  14. Gunderson LL, Tepper JE, Biggs PJ, et al. Intraoperative ± external beam irradiation. Curr. Probe Cancer, 7 (1983) 1–69.

    Article  CAS  Google Scholar 

  15. Gunderson LL, Cohen AM, Dosoretz DE, et al. Residual, unresectable or recurrent colorectal cancer: external beam irradiation and intraoperative electron beam boost ± resection. Int. Radiat. Oncol. Biol. Phys. 9 (1983) 1597–1606.

    Article  CAS  Google Scholar 

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© 1999 Springer Science+Business Media New York

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Nag, S., Gunderson, L.L., Willett, C.G., Harrison, L.B., Calvo, F.A. (1999). Intraoperative Irradiation with Electron-Beam or High-Dose-Rate Brachytherapy. In: Gunderson, L.L., Willet, C.G., Harrison, L.B., Calvo, F.A. (eds) Intraoperative Irradiation. Current Clinical Oncology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-696-6_7

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  • DOI: https://doi.org/10.1007/978-1-59259-696-6_7

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4757-5576-3

  • Online ISBN: 978-1-59259-696-6

  • eBook Packages: Springer Book Archive

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