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Physics of Intraoperative High-Dose-Rate Brachytherapy

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Book cover Intraoperative Irradiation

Part of the book series: Current Clinical Oncology ((CCO))

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Abstract

Intraoperative irradiation by high-dose-rate remote-afterloading brachytherapy (HDRIORT) requires, in addition to capabilities in surgery and radiation oncology, specialized physical equipment and facilities, appropriate computer software for treatment planning and, as an integral part of the interdisciplinary team, physicists trained in dose planning, dose delivery, and quality-assurance procedures. The rationale for HDR-IORT is related, in large part, to the physical advantages it affords of confining the therapeutic dose to a highly localized target and sparing normal structures either by moving them away or shielding them. These advantages may substantially offset the radiobiological disadvantage associated with a single-fraction treatment (see Chapter 2). Although only a few institutions are currently performing HDR-IORT, sufficient experience has been acquired to establish its feasibility with respect to such physical factors as available source strength, suitable applicators, and acceptable treatment durations.

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Authors
  1. Lowell L. Anderson
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  2. Patrick J. Harrington
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  3. Jean St. Germain
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Editor information

Editors and Affiliations

  1. Mayo Clinic and Mayo Medical School, Rochester, MN, USA

    Leonard L. Gunderson MD, MS (Professor and Chair of Oncology) (Professor and Chair of Oncology)

  2. Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA

    Christopher G. Willet MD

  3. Albert Einstein College of Medicine and Beth Israel Cancer Center, New York, NY, USA

    Louis B. Harrison MD

  4. University Hospital Gregorio Marañón, Madrid, Spain

    Felipe A. Calvo MD (Chair of Oncology) (Chair of Oncology)

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© 1999 Springer Science+Business Media New York

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Anderson, L.L., Harrington, P.J., Germain, J.S. (1999). Physics of Intraoperative High-Dose-Rate Brachytherapy. In: Gunderson, L.L., Willet, C.G., Harrison, L.B., Calvo, F.A. (eds) Intraoperative Irradiation. Current Clinical Oncology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-696-6_5

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  • DOI: https://doi.org/10.1007/978-1-59259-696-6_5

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4757-5576-3

  • Online ISBN: 978-1-59259-696-6

  • eBook Packages: Springer Book Archive

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