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Intraoperative Irradiation pp 471–497Cite as

IORT for Head and Neck Cancer

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Part of the book series: Current Clinical Oncology ((CCO))

Abstract

Current standard treatment for locally advanced but resectable (stages III and IV and selected stage II) head and neck cancer includes surgery combined with preoperative or postoperative radiation therapy or radiation therapy alone or combined with a neck dissection with surgery reserved for salvage. Chemotherapy may be added. However, other than a neoadjuvant role for organ preservation in advanced larynx or pyriform sinus cancer and a concomitant and maintenance role in advanced nasopharyngeal cancer, the role for chemotherapy remains to be defined (1–3). Despite advances made in recent years with combined modality therapy, local and regional recurrence rates remain unacceptably high (20–60%), and 5-year survival rates remain disappointingly low (30–60%).

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Authors
  1. Robert L. Foote
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  2. Peter Garrett
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  3. William Rate
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  4. Subir Nag
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  5. Rafael Martinez-Monge
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  6. Thierry Schmitt
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  7. Thomas V. McCaffrey
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Editor information

Editors and Affiliations

  1. Mayo Clinic and Mayo Medical School, Rochester, MN, USA

    Leonard L. Gunderson MD, MS (Professor and Chair of Oncology) (Professor and Chair of Oncology)

  2. Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA

    Christopher G. Willet MD

  3. Albert Einstein College of Medicine and Beth Israel Cancer Center, New York, NY, USA

    Louis B. Harrison MD

  4. University Hospital Gregorio Marañón, Madrid, Spain

    Felipe A. Calvo MD (Chair of Oncology) (Chair of Oncology)

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Foote, R.L. et al. (1999). IORT for Head and Neck Cancer. In: Gunderson, L.L., Willet, C.G., Harrison, L.B., Calvo, F.A. (eds) Intraoperative Irradiation. Current Clinical Oncology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-696-6_26

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  • DOI: https://doi.org/10.1007/978-1-59259-696-6_26

  • Publisher Name: Humana Press, Totowa, NJ

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